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open access

Cataract Preventive Role of Isolated Phytoconstituents: Findings from a Decade of Research

Description: This review aims to find effective phytoconstituents in cataract treatments in vitro, ex vivo, and in vivo. Scientists have focused their attention not only for anti-cataract activity in vitro, but also in ex vivo and in vivo from the review of active phytoconstituents in medicinal plants. In our present review, we identified 58 active phytoconstituents with strong anti-cataract effects at in vitro and ex vivo with lack of in vivo studies.
Date: October 26, 2018
Creator: Lim, Vuanghao; Schneider, Edward; Wu, Hongli & Pang, Iok-Hou
open access

Lipopolysaccharide Challenge Reveals Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Murine Systemic Lupus Erythematosus

Description: Study explores whether chronic inflammatory processes in systemic lupus erythematosus (SLE) are in part due to hypothalamic-pituitary-adrenal (HPA) axis dysfunction by challenging female control and SLE mice with lipopolysaccharide (LPS) and measuring c-Fos expression as an index of neuronal activation, plasma adrenocorticotrophic hormone (ACTH) as an index of anterior pituitary function, and plasma corticosterone as an index of adrenal function.
Date: October 4, 2018
Creator: Pham, Grace S. & Mathis, Keisa W.
open access

“Youth Are More Aware and Intelligent than Imagined”: The Mountain Air Youth Photovoice Project

Description: This article looks at respiratory illness in Appalachian Kentucky because it reports some of the highest rates of respiratory illness in the United States. As part of the Mountain Air Project, local youth were invited to share their perspectives on possible contributing factors to respiratory illness, and the authors undertook an exploratory study to determine the utility of photovoice to elicit such perspectives with this population. This study demonstrates the value of incorporating youth per… more
Date: October 11, 2019
Creator: Cardarelli, Katheryn M.; Paul, Marcy; May, Beverly; Dunfee, Madeline; Browning, Steven & Schoenberg, Nancy
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