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Flanking Variation Influences Rates of Stutter in Simple Repeats

Description: This article shows that rates of stutter can vary substantially depending on the flanking haplotype, and while there are cases where the LUS is a better predictor of stutter than the PAL, examples to the contrary are apparent in commonly assayed forensic markers. Further, flanking variation that is 7 bp from the repeat region can impact rates of stutter. These findings suggest that non-proximal effects, such as DNA secondary structure, may be impacting the rates of stutter in common forensic sh… more
Date: November 17, 2017
Creator: Woerner, August E.; King, Jonathan L. & Budowle, Bruce
Item Type: Refine your search to only Article
open access

Transitioning from Acute to Chronic Pain: An Examination of Different Trajectories of Low-Back Pain

Description: The article examines the most recent trajectory research, and highlights the importance of developing a broader model for patient evaluation. Traditionally, there has been a widely accepted notion that the transition from acute to chronic pain follows a linear trajectory, where an injury leads to acute episodes, subacute stages, and progresses to a chronic pain condition. However, it appears that pain progression is much more complicated and individualized than this original unsupported assumpt… more
Date: May 17, 2018
Creator: Gatchel, Robert J.; Bevers, Kelley; Licciardone, John C.; Su, Jianzhong; Du, Ying & Brotto, Marco
Item Type: Refine your search to only Article
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