Search Results

open access

Activation of an S6/H4 Kinase (PAK 65) from Human Placenta by Intramolecular and Intermolecular Autophosphorylation

Description: Article proposing a model in which phosphorylation of sites 1 and 2 occurs sequentially. The model proposes that trypsin treatment of the inactive holoenzyme removes an inhibitory rac-binding domain which blocks MgATP access to the catalytic site. The pseudosubstrate domain at site 1 is autophosphorylated and subsequent bimolecular autophosphorylation at site 2 fully opens the catalytic site.
Date: September 8, 1995
Creator: Benner, Gretchen E.; Dennis, Patrick B. & Masaracchia, Ruthann A.
open access

N-acylethanolamide metabolizing enzymes are upregulated in human neural progenitor-derived neurons exposed to sub-lethal oxidative stress

Description: Article is a study determining whether ReN cells, a superior cell model system for studying neurodevelopment, differentiation, and neuroprotection, express proteins involved in canonical eCB NAE signaling and whether oxidative stress can induce their expression. This study is a first step toward determining how oxidative stress affects CB1, CB2, FAAH, NAAA, and NAPE-PLD expression and their potential defense against oxidative stress.
Date: August 8, 2022
Creator: Duncan, Scott R.; Riordan, Sean M.; Hall, Conner W.; Payne, Andrew J.; Chapman, Kent Dean & Koulen, Peter
open access

AFLOW-QHA3P: Robust and automated method to compute thermodynamic properties of solids

Description: Article introducing the quasiharmonic approximation three-phonon method to calculate the thermodynamic properties of both nonmetallic and metallic compounds. This study demonstrates that QHA3P is an ideal framework for the high-throughput prediction of finite-temperature material properties, combining the accuracy of QHA with the computational efficiency of SC-QHA.
Date: July 8, 2019
Creator: Nath, Pinku; Usanmaz, Demet; Hicks, David; Oses, Corey; Fornari, Marco; Buongiorno Nardelli, Marco et al.
open access

Case report: Early-onset osteoporosis in a patient carrying a novel heterozygous variant of the WNT1 gene

Description: Article presents a case study of a 35 year-old Caucasian woman who experienced multiple vertebral fractures two months after her second pregnancy. The results suggest a potential role of heterozygous WNT1 variants in the pathogenesis of early-onset osteoporosis. The authors suggest that teriparatide is one of the most appropriate available therapies for such cases.
Date: August 8, 2022
Creator: Campopiano, Maria Cristina; Fogli, Antonella; Michelucci, Angela; Mazoni, Laura; Longo, Antonella; Borsari, Simona et al.
open access

Comments on “Thermodynamic modeling studies of aqueous solubility of caffeine, gallic acid and their cocrystal in the temperature range of 303 Ke363 K”

Description: This article comments on activity coefficients based on a thermodynamic relationship that failed to properly take into account the solid phase transition that both caffeine and gallic acid exhibited prior to melting.
Date: February 8, 2018
Creator: Acree, William E. (William Eugene)
open access

Corrigendum: The Differences Between Malate Dehydrogenase Malic Enzymes and Nicotinamide Adenine Dinucleotide Phosphate Malic Enzymes Subtypes of C₄ Photosynthesis: More Than Decarboxylating Enzymes

Description: This is a correction of a previously released article. A mistake was found in Figure 2 of the published work. The names of the cell types, “mesophyll cell” and “bundle sheath” were erroneously interchanged.
Date: March 8, 2019
Creator: Rao, Xiaolan & Dixon, R. A.
open access

Embryonic developmental oxygen preconditions cardiovascular functional response to acute hypoxic exposure and maximal β-adrenergic stimulation of anesthetized juvenile American alligators (Alligator mississippiensis)

Description: Article investigating the effect of embryonic hypoxia on the cardiovascular phenotype of 4-year-old American alligators (Alligator mississippiensis). The findings indicate that embryonic hypoxia in crocodilians alters the cardiovascular phenotype, changing the juvenile response to acute hypoxia and β-adrenergic stimulation.
Date: November 8, 2019
Creator: Smith, Brandt R.; Crossley, Janna; Elsey, Ruth M.; Hicks, James W. & Crossley, Dane A., II
open access

Event-Driven Deep Learning for Edge Intelligence (EDL-EI)

Description: Article on deep-learning framework for edge intelligence EDL-EI (event-driven deep learning for edge intelligence). To verify the proposed framework, the authors include a case study of air-quality scenarios based for the most polluted cities in South Korea and China.
Date: September 8, 2021
Creator: Shah, Sayed Khushal; Tariq, Zeenat; Lee, Jeehwan & Lee, Yugyung
open access

Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Description: Article investigating if the exposure to diesel exhaust particles (DEP) can alter commensal lung microbiota, thereby promoting alterations in the lung’s immune and inflammatory responses. This article also explores if diet contributes to the alteration of the commensal lung microbiome.
Date: January 8, 2021
Creator: Daniel, Sarah; Phillippi, Danielle; Schneider, Leah J.; Nguyen, Kayla N.; Mirpuri, Julie & Lund, Amie K.
open access

Exposure to diesel exhaust particulates and desert sand dust generates microvesicle particles and platelet-activating factor agonists

Description: The authors address the editor in their article, stating that the majority of the general population, particularly, servicemen and women deployed across the globe are exposed to various airborne hazards, including diesel exhaust particulate (DEP) and desert sand dust (DSD). Studies, including the author's study, have shown that exposure to ROS-generating pro-oxidative stressors ranging from environmental carcinogens to pollutants, including cigarette smoke, produces a class of potent phospholip… more
Date: April 8, 2023
Creator: Thyagarajan, Anita; Rapp, Christine M.; Schneider, Leah; Lund, Amie K.; Travers, Jeffrey B. & Sahu, Ravi P.

Flipped and Free: an inverted, active-learning general chemistry course using exclusively OER

Description: Presentation on using a flipped course format and including an open textbook, OpenStax: Chemistry 2e. Flipped courses provide lecture content that is accessible online, and they use class time for active learning activities. It is a part of 2022 University of North Texas Open Access Symposium that was held on March 8, 2022.
Date: March 8, 2022
Creator: Petros, Amy K.
open access

Giant spin Hall effect in two-dimensional monochalcogenides

Description: This article, using calculations from first principles, reveals for the first time giant intrinsic spin Hall conductivities (SHC) in these materials. In particular, the article shows that the SHC resonances can be easily tuned by combination of strain and doping and, in some cases, strain can be used to induce semiconductor to metal transition that makes a giant spin Hall effect possible even in absence of doping.
Date: February 8, 2019
Creator: Sławińska, Jagoda; Cerasoli, Frank T.; Wang, Haihang; Postorino, Sara; Supka, Andrew; Curtarolo, Stefano et al.
open access

Growth of Highly-Ordered Metal Nanoparticle Arrays in the Dimpled Pores of an Anodic Aluminum Oxide Template

Description: Article presents a reliable, scalable, and inexpensive technology for the fabrication of ordered arrays of metal nanoparticles with large areal coverage on various substrates. Using a simple model, the experimental results were interpreted and supported by numerical estimations.
Date: November 8, 2022
Creator: Farmer, Gavin; Abraham, James; Littler, Chris; Syllaios, A. J. & Philipose, Usha
open access

In silico guided structural and functional analysis of genes with potential involvement in resistance to coffee leaf rust: A functional marker based approach

Description: Article presents novel insights into the molecular nature of the SH genes, thereby opening new avenues for coffee rust resistance molecular breeding.
Date: July 8, 2020
Creator: Ferreira, Svio Siqueira; Barka, Geleta Dugassa; Caixeta, Eveline Teixeira & Zambolim, Larcio
open access

Influence of coherent population trapping on Raman scattering

Description: Article considering the Raman scattering in molecular media. Applying two laser fields in a two-photon resonance with vibrational transition, the authors study the role of rotational levels for excitation of vibrational coherence. It is shown that the molecular vibrational coherence strongly depends on the effect of coherent population trapping for rotational levels. The obtained results are important for applications of Raman spectroscopy to molecular detection in engineering, chemical, and bi… more
Date: August 8, 2019
Creator: Singh, Pooja; Rostovtsev, Yuri V.; Patnaik, Anil K.; Roy, Sukesh & Gord, James R.
open access

Jasmonic Acid Is Required for Plant Acclimation to a Combination of High Light and Heat Stress

Description: Article studying the responses of Arabidopsis (Arabidopsis thaliana) plants to a combination of high light and heat stress (HL+HS) conditions. The study reveals that Jasmonic acid (JA) plays an important role in the acclimation of plants to a combination of HL+HS.
Date: October 8, 2019
Creator: Sengupta, Soham; Azad, Rajeev K.; Balfagón, Damián; Gómez-Cadenas, Aurelio; Fritschi, Felix B.; Mittler, Ron et al.
open access

POSMM: an efficient alignment-free metagenomic profiler that complements alignment-based profiling

Description: Article presents POSMM, Python-Optimized Standard Markov Model classifier, which is a new incarnation of the Markov model approach to metagenomic sequence analysis. The authors claim that by combining POSMM with ultrafast classifiers such as Kraken2, their complementary strengths can be leveraged to produce higher overall accuracy in metagenomic sequence classification than by either as a standalone classifier. POSMM is a user-friendly and highly adaptable tool designed for broad use by the met… more
Date: March 8, 2023
Creator: Burks, David J.; Pusadkar, Vaidehi & Azad, Rajeev K.
open access

Reference materials for phase equilibrium studies. 1. Liquid–liquid equilibria (IUPAC Technical Report)

Description: This article is the first of three projected IUPAC Technical Reports resulting from IUPAC Project 2011-037-2-100 (Reference Materials for Phase Equilibrium Studies). This report proposes seven systems for liquid–liquid equilibrium studies, covering the four most common categories of binary mixtures: aqueous systems of moderate solubility, non-aqueous systems, systems with low solubility, and systems with ionic liquids.
Date: July 8, 2021
Creator: Bazyleva, Ala; Acree, William E. (William Eugene); Chirico, Robert D.; Diky, Vladimir; Hefter, Glenn T.; Jacquemin, Johan et al.
open access

Silicon versus Superbug: Assessing Machine Learning's Role in the Fight against Antimicrobial Resistance

Description: Article describes how, in his 1945 Nobel Prize acceptance speech, Sir Alexander Fleming warned of antimicrobial resistance (AMR) if the necessary precautions were not taken diligently. This paper explores the applications of ML in predicting and understanding AMR, highlighting its potential in revolutionizing healthcare practices.
Date: November 8, 2023
Creator: Coxe, Tallon & Azad, Rajeev K.
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