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Improved radioimmunotherapy of hematologic malignancies

Description: This research project proposes to develop novel new approaches of improving the radioimmunodetection and radioimmunotherapy of malignancies by augmenting retention of radioimmunoconjugates by tumor cells. The approaches shown to be effective in these laboratory experiments will subsequently be incorporated into out ongoing clinical trials in patients. Specific project objectives include: to study the rates of endocytosis, intracellular routing, and metabolic degradation of radiolabeled monoclon… more
Date: March 24, 1992
Creator: Press, O.W.
Partner: UNT Libraries Government Documents Department
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Beam test of a large area silicon drift detector

Description: The results from the tests of the first large area (4 [times] 4 cm[sup 2]) planar silicon drift detector prototype in a pion beam are reported. The measured position resolution in the drift direction is ([sigma]=40 [plus minus] 10)[mu]m.
Date: March 24, 1992
Creator: Castoldi, A.; Chinnici, S.; Gatti, E.; Longoni, A.; Palma, F.; Sampietro, M. (Consiglio Nazionale delle Ricerche, Milan (Italy)) et al.
Partner: UNT Libraries Government Documents Department
open access

Beam test of a large area silicon drift detector

Description: The results from the tests of the first large area (4 {times} 4 cm{sup 2}) planar silicon drift detector prototype in a pion beam are reported. The measured position resolution in the drift direction is ({sigma}=40 {plus_minus} 10){mu}m.
Date: March 24, 1992
Creator: Castoldi, A.; Chinnici, S.; Gatti, E.; Longoni, A.; Palma, F.; Sampietro, M. et al.
Partner: UNT Libraries Government Documents Department
open access

Improved Radioimmunotherapy of Hematologic Malignancies. [Final Report]

Description: This research project proposes to develop novel new approaches of improving the radioimmunodetection and radioimmunotherapy of malignancies by augmenting retention of radioimmunoconjugates by tumor cells. The approaches shown to be effective in these laboratory experiments will subsequently be incorporated into out ongoing clinical trials in patients. Specific project objectives include: to study the rates of endocytosis, intracellular routing, and metabolic degradation of radiolabeled monoclon… more
Date: March 24, 1992
Creator: Press, Oliver W.
Partner: UNT Libraries Government Documents Department
open access

Visualization of high resolution, three-dimensional, nonlinear finite element analyses

Description: A two-pass surface extraction algorithm for adaptive finite element meshes is presented in the context of a visualization study for a particle impact and a turbine containment problem. The direct use of finite element data structures for the computation of external surfaces, surface normals, and derived physical quantities is discussed. An overview of the in-betweening algorithm which compensates for rigid body dynamics is presented with a brief discussion of a {open_quotes}direct-to-videodisk{… more
Date: March 24, 1992
Creator: Christon, M. A. & Spelce, T. E.
Partner: UNT Libraries Government Documents Department
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Recent Developments in Japan's HDR Program

Description: Japan is one of the most active volcanic countries in the world, and it is understood to have very abundant geothermal energy. In Japan, where only a limited amount of other natural energy resources are domestically available, geothermal energy is one of the nation's purely indigenous energy sources. Its development therefore, has, been anxiously urged. Geothermal energy is classified generally in several types: vapor dominated type resources, which are mainly used to generate electric power, a… more
Date: March 24, 1992
Creator: Yamaguchi, Tsutomu
Partner: UNT Libraries Government Documents Department
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Optimizing Reinjection Strategy at Palinpinon, Philippines Based on Chloride Data

Description: One of the guidelines established for the safe and efficient management of the Palinpinon Geothermal Field is to adopt a production and well utilization strategy such that the rapid rate and magnitude of reinjection fluid returns leading to premature thermal breakthrough would be minimized. To help achieve this goal, sodium fluorescein and radioactive tracer tests have been conducted to determine the rate and extent of communication between the reinjection and producing sectors of the field. Th… more
Date: March 24, 1992
Creator: Urbino, Ma. Elena G. & Horne, Roland N.
Partner: UNT Libraries Government Documents Department
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Reservoir Modeling and Prediction at Pleasant Bayou Geopressured-Geothermal Reservoir

Description: Modeling and prediction of geopressured-geothermal reservoirs is an excellent example of an engineering problem that can be solved through many different means. The problem may be approached from a purely numerical viewpoint, where a successful history match ''demonstrates'' the validity of the reservoir model, or from an analytical point of view. Each method has its own inherent limitations and weaknesses. Such limitations can be minimized by using some combination of both numerical and analyt… more
Date: March 24, 1992
Creator: Shook, Mike
Partner: UNT Libraries Government Documents Department
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Options in the Eleventh Year for Interim Standard Offer Number Four Contracts

Description: The Interim Standard Offer Number Four Contracts (ISM), under which most of the geothermal industry is selling power (outside of The Geysers), has an initial ten year period of known fixed energy payments. In the eleventh year, the price goes to the Avoided Cost of the buying utility. The specific contract language is ''Seller will be paid at a rate equal to the utilities' published avoided cost of energy as updated and authorized by the Commission (CPUC)''. The first geothermal contract will r… more
Date: March 24, 1992
Creator: Hinrichs, Thomas C.
Partner: UNT Libraries Government Documents Department
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Geologic Results from the Long Valley Exploratory Well

Description: As a deep well in the center of a major Quaternary caldera, the Long Valley Exploratory Well (LVEW) provides a new perspective on the relationship between hydrothermal circulation and a large crustal magma chamber. It also provides an important test of models for the subsurface structure of active continental calderas. Results will impact geothermal exploration, assessment, and management of the Long Valley resource and should be applicable to other igneous-related geothermal systems. Our task … more
Date: March 24, 1992
Creator: McConnell, Vicki S.; Eichelberger, John C.; Keskinen, Mary J. & Layer, Paul W.
Partner: UNT Libraries Government Documents Department
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Reservoir Technology

Description: The reservoir technology program supports the utilization of geothermal resources through development and verification of new earth science technologies for: exploration, fluid production and injection; and prediction of reservoir lifetimes. A two-fold strategy of conducting DOE-sponsored research to meet higher-risk, longer-term needs and cost-shared research with industry in areas of greatest current need is utilized to maximize the benefit of the program to the geothermal industry. The progr… more
Date: March 24, 1992
Creator: Renner, J.L.
Partner: UNT Libraries Government Documents Department
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Geothermal Geophysical Research in Electrical Methods at UURI

Description: The principal objective of electrical geophysical research at UURI has been to provide reliable exploration and reservoir assessment tools for the shallowest to the deepest levels of interest in geothermal fields. Three diverse methods are being considered currently: magnetotellurics (MT, and CSAMT), self-potential, and borehole resistivity. Primary shortcomings in the methods addressed have included a lack of proper interpretation tools to treat the effects of the inhomogeneous structures ofte… more
Date: March 24, 1992
Creator: Wannamaker, Philip E. & Wright, Phillip M.
Partner: UNT Libraries Government Documents Department
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Hydrothermal Energy Conversion Technology

Description: The goal of the Hydrothermal Program is to develop concepts which allow better utilization of geothermal energy to reduce the life-cycle cost of producing electricity from liquid-dominated, hydrothermal resources. Research in the program is currently ongoing in three areas: (1) Heat Cycle Research, which is looking at methods to increase binary plant efficiencies; (2) Materials Development, which is developing materials for use in geothermal associated environments; and (3) Advanced Brine Chemi… more
Date: March 24, 1992
Creator: Robertson, David W. & LaSala, Raymond J.
Partner: UNT Libraries Government Documents Department
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HDR Opportunities and Challenges Beyond the Long-Term Flow Test

Description: The long term flow test (LTFT) of the worlds largest, deepest, and hottest hot dry rock (HDR) reservoir currently underway at Fenton Hill, NM, is expected to demonstrate that thermal energy can be mined from hot rock within the earth on a sustainable basis with minimal water consumption. This test will simulate the operations of a commercial facility in some ways, but it will not show that energy from HDR can be produced at a variety of locations with different geological settings. Since the Fe… more
Date: March 24, 1992
Creator: Duchane, David
Partner: UNT Libraries Government Documents Department
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Critique of Drilling Research

Description: For a number of years the Department of Energy has been funding research to reduce the cost of drilling geothermal wells. Generally that research has been effective and helped to make geothermal energy economically attractive to developers. With the increased competition for the electrical market, geothermal energy needs every advantage it can acquire to allow it to continue as a viable force in the marketplace. In drilling related research, there is essentially continuous dialogue between indu… more
Date: March 24, 1992
Creator: Hamblin, Jerry
Partner: UNT Libraries Government Documents Department
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The Long Valley Well - Phase II Operations

Description: Phase II of the Long Valley Exploratory Well was completed to a depth of 7588 feet in November 1991. The drilling comprised two sub-phases: (1) drilling 17-1/2 inch hole from the Phase I casing shoe at 2558 feet to a depth of 7130 feet, plugging back to 6826 feet, and setting 13-3/8 inch casing at 6825 feet, all during August-September 1991; and (2) returning in November to drill a 3.85-inch core hole deviated out of the previous wellbore at 6808 feet and extending to 7588 feet. Ultimate depth … more
Date: March 24, 1992
Creator: Finger, John T.
Partner: UNT Libraries Government Documents Department
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Geothermal Energy Market in Southern California Past, Present and Future

Description: I'm pleased to be here as your keynote speaker from the utility industry. Today is fitting to discuss the role of an alternative/renewable energy resource such as geothermal. Three years ago today, the Exxon Valdez oil tanker spilled 11 million gallons of oil into Prince William Sound, Alaska. This ecological catastrophe was another of those periodic jolts that underscores the importance of lessening our nation's dependence on oil and increasing the use of cost-effective, environmentally benign… more
Date: March 24, 1992
Creator: Budhraja, Vikram S.
Partner: UNT Libraries Government Documents Department
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Geothermal Waste Treatment Biotechnology: Progress and Advantages to the Utilities

Description: Development of biotechnology for treatment of geothermal residual waste is aimed at the application of low-cost biochemical processes for the surface treatment and disposal of residual geothermal sludges. These processes, in addition to the lowering of disposal cost, are designed to be environmentally acceptable. Recent studies at Brookhaven National Laboratory (BNL) have shown that optimization of several process variables results in fast rates (<24h) of metal removal from residual sludges … more
Date: March 24, 1992
Creator: Premuzic, E.T.; Lin, M.S. & Jin, J.
Partner: UNT Libraries Government Documents Department
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Downhole Memory-Logging Tools

Description: Logging technologies developed for hydrocarbon resource evaluation have not migrated into geothermal applications even though data so obtained would strengthen reservoir characterization efforts. Two causative issues have impeded progress: (1) there is a general lack of vetted, high-temperature instrumentation, and (2) the interpretation of log data generated in a geothermal formation is in its infancy. Memory-logging tools provide a path around the first obstacle by providing quality data at a… more
Date: March 24, 1992
Creator: Lysne, Peter
Partner: UNT Libraries Government Documents Department
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NGA Industry Critique of the Exploration Component

Description: The author critiques the Exploration component of the U.S. Department of Energy (DOE) Geothermal Program Review X. The comments focus principally on the hydrothermal portion of the DOE program, but he also makes some commentary on the Long Valley Exploratory Well and Geopressured-Geothermal components of the program, as well as some general comments. Before I do that, I would like to review the current state of geothermal exploration in the United States. According to Koenig (1989, 1990) who cr… more
Date: March 24, 1992
Creator: Iovanetti, J.L.
Partner: UNT Libraries Government Documents Department
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Technology Advancements to Support Growth in Geothermal Power Sales in a Dynamic Utility Market

Description: We are assembled today to discuss the opportunities and challenges for expanding the sales of geothermally-generated electric power in a competitive utility market. First, however, I would like to note that growth in geothermal sales might not be a germane topic were it not for the early participation in the development of the geothermal industry by utilities themselves. Without their contributions to research and development, environmental breakthroughs, and, perhaps, above all, their early us… more
Date: March 24, 1992
Creator: Mock, John E.
Partner: UNT Libraries Government Documents Department
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Materials for Geothermal Production

Description: Advances in the development of new materials continue to be made in the Geothermal Materials Project. Many successes have already been accrued and the results used commercially. In FY 1991, work was focused on reducing well drilling, fluid transport and energy conversion costs. Specific activities performed included lightweight CO{sub 2}-resistant well cements, thermally conductive and scale resistant protective liner systems, chemical systems for lost circulation control, corrosion mitigation … more
Date: March 24, 1992
Creator: Kukacka, Lawrence E.
Partner: UNT Libraries Government Documents Department
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Geothermal Brine Chemistry Modeling Program

Description: The UCSD brine chemistry program is providing highly accurate models of the behavior of high temperature brines to be used by the geothermal community to optimize production, interpret formation behavior and assist in performance assessment. Models are now available as user-oriented programs packaged for both main frame and personal computers (IBM and Macintosh). A manual describing the models and their application to various geothermal problems has been developed and made available to potentia… more
Date: March 24, 1992
Creator: Duan, Zhenhao; Moller, Nancy; Greenberg, Jerry & Weare, John H.
Partner: UNT Libraries Government Documents Department
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Lost Circulation Technology Development Status

Description: Lost circulation is the loss of drilling fluid from the wellbore to fractures or pores in the rock formation. In geothermal drilling, lost circulation is often a serious problem that contributes greatly to the cost of the average geothermal well. The Lost Circulation Technology Development Program is sponsored at Sandia National Laboratories by the U.S. Department of Energy. The goal of the program is to reduce lost circulation costs by 30-50% through the development of mitigation and character… more
Date: March 24, 1992
Creator: Glowka, David A.; Schafer, Diane M.; Loeppke, Glen E.; Scott, Douglas D.; Wernig, Marcus D. & Wright, Elton K.
Partner: UNT Libraries Government Documents Department
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