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CYP1B1 expression, a potential risk factor for breast cancer

Description: CYP1B1 expression in non-tumor breast tissue from breast cancer patients and cancer-free individuals was determined to test the hypothesis that high CYP1B1 expression is a risk factor for breast cancer. Large interindividual variations in CYP1B1 expression were found with CYP1B1 levels notably higher in breast cancer patients than cancer-free individuals. The results indicate that CYP1B1 might play a role in breast cancer either through increased PAH activation or through metabolism of endogeno… more
Date: May 31, 2001
Creator: Goth-Goldstein, Regine; Erdmann, Christine A. & Russell, Marion
Partner: UNT Libraries Government Documents Department

Solvation descriptors for pesticides from the solubility of solids: diuron as an example

Description: Article on the solvation descriptors for pesticides from the solubility of solids and diuron as an example.
Access: Restricted to UNT Community Members. Login required if off-campus.
Date: November 23, 2000
Creator: Green, Caroline E.; Abraham, M. H. (Michael H.); Acree, William E. (William Eugene); De Fina, Karina M. & Sharp, Tina L.
Partner: UNT College of Arts and Sciences
open access

Efficiency of clay-TiO2 nanocomposites on the photocatalytic eliminationof a model hydrophobic air pollutant

Description: Clay-supported TiO2 photocatalysts can potentially improve the performance of air treatment technologies via enhanced adsorption and reactivity of target volatile organic compounds (VOCs). In this study, a bench-top photocatalytic flow reactor was used to evaluate the efficiency of hectorite-TiO2 and kaolinite-TiO2, two novel composite materials synthesized in our laboratory. Toluene, a model hydrophobic VOC and a common indoor air pollutant, was introduced in the air stream at realistic concen… more
Date: January 1, 2009
Creator: Kibanova, Daria; Cervini-Silva, Javiera & Destaillats, Hugo
Partner: UNT Libraries Government Documents Department
open access

Crystallization of Mitochondrial Respiratory Complex II fromChicken Heart: A Membrane-Protein Complex Diffracting to 2.0Angstrom

Description: Procedure is presented for preparation of diffraction-quality crystals of a vertebrate mitochondrial respiratory Complex II. The crystals have the potential to diffract to at least 2.0 Angstrom with optimization of post-crystal-growth treatment and cryoprotection. This should allow determination of the structure of this important and medically relevant membrane protein complex at near-atomic resolution and provide great detail of the mode of binding of substrates and inhibitors at the two subst… more
Date: December 17, 2004
Creator: Huang, Li-shar; Borders, Toni M.; Shen, John T.; Wang, Chung-Jen & Berry, Edward A.
Partner: UNT Libraries Government Documents Department
open access

Spontaneous Brain Activity as a Source of Ideal 1/f Noise

Description: In this article, the authors study the electroencephalogram (EEG) of 30 closed-eye subjects with a technique of analysis recently proposed to detect punctual events signaling rapid transitions between different metastable states.
Date: December 18, 2009
Creator: Allegrini, Paolo; Menicucci, Danilo; Bedini, Remo; Fronzoni, Leone; Gemignani, Angelo; Grigolini, Paolo et al.
Partner: UNT College of Arts and Sciences
open access

Kinetics of phase growth in the Cu-Sn system and application to composite Nb3Sn strands

Description: Nb{sub 3}Sn is the superconductor most used in the R and D of high field accelerator magnets by either the wind and react or the react and wind technique. In order to program the low temperature steps of the heat treatment, the growth kinetics of Cu-Sn intermetallics was investigated as a function of duration and temperature. The diffusion constants of {eta}, {var_epsilon} and {delta} phases between 150 and 550 C were evaluated using Cu-Sn model samples. Statistical and systematic errors were t… more
Date: November 18, 2002
Creator: al.1, Emanuela Barzi et
Partner: UNT Libraries Government Documents Department
open access

New Data and File Requirements for Tet-1

Description: A new version of Tet- is being finalized for distribution and beta-testing. The new version allows the user to create and modify the TETRAD input deck either graphically or manually. By defining Regions within the TETRAD domain and defining parameters within the regions, parameter estimation is done external to any proprietary software. The new version of Tet-1 can be run on any existing version of TETRAD, and makes identifying the TETRAD parameters to be estimated easier and more general than … more
Date: January 1, 2003
Creator: Shook, G. Michael
Partner: UNT Libraries Government Documents Department
open access

Downregulation of Protein 4.1R impairs centrosome function,bipolar spindle organization and anaphase

Description: Centrosomes nucleate and organize interphase MTs and areinstrumental in the assembly of the mitotic bipolar spindle. Here wereport that two members of the multifunctional protein 4.1 family havedistinct distributions at centrosomes. Protein 4.1R localizes to maturecentrioles whereas 4.1G is a component of the pericentriolar matrixsurrounding centrioles. To selectively probe 4.1R function, we used RNAinterference-mediated depletion of 4.1R without decreasing 4.1Gexpression. 4.1R downregulation r… more
Date: March 17, 2006
Creator: Spence, Jeffrey R.; Go, Minjoung M.; Bahmanyar, S.; Barth,A.I.M. & Krauss, Sharon Wald
Partner: UNT Libraries Government Documents Department
open access

Progress in Photovoltaic Components and Systems

Description: The Photovoltaic Manufacturing Research and Development project is a government/industry partnership between the US Department of Energy and members of the US photovoltaic (TV) industry. The purpose of the project is to work with industry to improve manufacturing processes, reduce manufacturing costs, and improve the performance of PV products. This project is conducted through phased solicitations with industry participants selected through a competitive evaluation process. Starting in 1995, t… more
Date: July 15, 2000
Creator: Thomas, H.; Kroposki, B.; Witt, C. & Bower, Ward I.
Partner: UNT Libraries Government Documents Department
open access

The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells

Description: The mammary gland develops its adult form by a process referred to as branching morphogenesis. Many factors have been reported to affect this process. We have used cultured primary mammary epithelial organoids and mammary epithelial cell lines in three-dimensional collagen gels to elucidate which growth factors, matrix metalloproteinases (MMPs) and mammary morphogens interact in branching morphogenesis. Branching stimulated by stromal fibroblasts, epidermal growth factor, fibroblast growth fact… more
Date: March 6, 2002
Creator: Simian, M.; Harail, Y.; Navre, M.; Werb, Z.; Lochter, A. & Bissell, M.J.
Partner: UNT Libraries Government Documents Department
open access

Visualization of a Deterministic Radiation Transport Model Using Standard Visualization Tools

Description: Output from a deterministic radiation transport code running on a CRAY SV1 is imported into a standard distributed, parallel, visualization tool for analysis. Standard output files, consisting of tetrahedral meshes, are imported to the visualization tool through the creation of a application specific plug-in module. Visualization samples are included, providing visualization of steady state results. Different plot types and operators are utilized to enhance the analysis and assist in reporting … more
Date: May 1, 2004
Creator: Galbraith, James A. & Greenwade, L. Eric
Partner: UNT Libraries Government Documents Department
open access

Multiplicative or t1 Noise in NMR Spectroscopy

Description: The signal in an NMR experiment is highly sensitive to fluctuations of the environment of the sample. If, for example, the static magnetic field B{sub 0}, the amplitude and phase of radio frequency (rf) pulses, or the resonant frequency of the detection circuit are not perfectly stable and reproducible, the magnetic moment of the spins is altered and becomes a noisy quantity itself. This kind of noise not only depends on the presence of a signal, it is in fact proportional to it. Since all the … more
Date: January 25, 2005
Creator: Granwehr, Josef
Partner: UNT Libraries Government Documents Department
open access

Insertion of a self-splicing intron into the mtDNA of atriploblastic animal

Description: Nephtys longosetosa is a carnivorous polychaete worm that lives in the intertidal and subtidal zones with worldwide distribution (pleijel&rouse2001). Its mitochondrial genome has the characteristics typical of most metazoans: 37 genes; circular molecule; almost no intergenic sequence; and no significant gene rearrangements when compared to other annelid mtDNAs (booremoritz19981995). Ubiquitous features as small intergenic regions and lack of introns suggested that metazoan mtDNAs are under … more
Date: April 14, 2006
Creator: Valles, Y.; Halanych, K. & Boore, J.L.
Partner: UNT Libraries Government Documents Department
open access

More modular invariant anomalous U(1) breaking

Description: We consider the case of several scalar fields, charged under a number of U(1) factors, acquiring vacuum expectation values due to anomalous U(1). We demonstrate how to make redefinitions at the superfield level in order to account for tree-level exchange of vector supermultiplets in the effective supergravity theory of the light fields in the supersymmetric vacuum phase. Our approach builds up on previous results that we obtained in a more elementary case. We find that the modular weights of li… more
Date: June 27, 2002
Creator: Gaillard, Mary K. & Giedt, Joel
Partner: UNT Libraries Government Documents Department
open access

Protein-Nanocrystal Conjugates Support a Single Filament Polymerization Model in R1 Plasmid Segregation

Description: To ensure inheritance by daughter cells, many low-copy number bacterial plasmids, including the R1 drug-resistance plasmid, encode their own DNA segregation systems. The par operon of plasmid R1 directs construction of a simple spindle structure that converts free energy of polymerization of an actin-like protein, ParM, into work required to move sister plasmids to opposite poles of rod-shaped cells. The structures of individual components have been solved, but little is known about the ultrast… more
Date: July 15, 2008
Creator: Choi, Charina L.; Claridge, Shelley A.; Garner, Ethan C.; Alivisatos, A. Paul & Mullins, R. Dyche
Partner: UNT Libraries Government Documents Department
open access

An alkyne metathesis-based route toortho-dehydrobenzannulenes

Description: An application of alkyne metathesis to 1,2-di(prop-1-ynyl)arenes, producing dehydrobenzannulenes, is described. An efficient method for selective Sonogashira couplings of bromoiodoarenes under conditions of microwave irradiation is also reported.
Date: November 7, 2002
Creator: Miljanic, Ognjen S.; Vollhardt, Peter C. & Whitener, Glenn D.
Partner: UNT Libraries Government Documents Department
open access

Proton hexality from an anomalous flavor U(1) and neutrino masses--Linking to the string scale

Description: We devise minimalistic gauged U(1)_X Froggatt-Nielsen models which at low-energy give rise to the recently suggested discrete gauge Z_6 symmetry, proton hexality, thus stabilizing the proton. Assuming three generations of right-handed neutrinos, with the proper choice of X-charges, we obtain viable neutrino masses. Furthermore, we find scenarios such that no X-charged hidden sector superfields are needed, which from a bottom-up perspective allows the calculation of g_string, g_X and G_SM's … more
Date: August 7, 2007
Creator: Murayama, Hitoshi; Dreiner, Herbi K.; Luhn, Christoph; Murayama, Hitoshi & Thormeiere, Marc
Partner: UNT Libraries Government Documents Department
open access

The BARD1 C-Terminal Domain Structure and Interactions with Polyadenylation Factor CstF-50

Description: The BARD1 N-terminal RING domain binds BRCA1 while the BARD1 C-terminal ankyrin and tandem BRCT repeat domains bind CstF-50 to modulate mRNA processing and RNAP II stability in response to DNA damage. Here we characterize the BARD1 structural biochemistry responsible for CstF- 50 binding. The crystal structure of the BARD1 BRCT domain uncovers a degenerate phosphopeptide binding pocket lacking the key arginine required for phosphopeptide interactions in other BRCT proteins.Small angle X-ray sca… more
Date: July 13, 2009
Creator: Edwards, Ross A.; Lee, Megan S.; Tsutakawa, Susan E.; Williams, R. Scott; Tainer, John A. & Glover, J. N. Mark
Partner: UNT Libraries Government Documents Department
open access

User and Performance Impacts from Franklin Upgrades

Description: The NERSC flagship computer Cray XT4 system"Franklin" has gone through three major upgrades: quad core upgrade, CLE 2.1 upgrade, and IO upgrade, during the past year. In this paper, we will discuss the various aspects of the user impacts such as user access, user environment, and user issues etc from these upgrades. The performance impacts on the kernel benchmarks and selected application benchmarks will also be presented.
Date: May 10, 2009
Creator: He, Yun (Helen)
Partner: UNT Libraries Government Documents Department
open access

Performance Characteristics of an Adaptive Mesh RefinementCalculation on Scalar and Vector Platforms

Description: Adaptive mesh refinement (AMR) is a powerful technique thatreduces the resources necessary to solve otherwise in-tractable problemsin computational science. The AMR strategy solves the problem on arelatively coarse grid, and dynamically refines it in regions requiringhigher resolution. However, AMR codes tend to be far more complicatedthan their uniform grid counterparts due to the software infrastructurenecessary to dynamically manage the hierarchical grid framework. Despitethis complexity, it… more
Date: January 31, 2006
Creator: Welcome, Michael; Rendleman, Charles; Oliker, Leonid & Biswas, Rupak
Partner: UNT Libraries Government Documents Department
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