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open access

Deep learning for peptide identification from metaproteomics datasets

Description: This article explores a proposed deep-learning-based algorithm called DeepFilter for improving peptide identifications from a collection of tandem mass spectra. The authors find that DeepFilter is believed to generalize properly to new, previously unseen peptide-spectrum-matches and can be readily applied in peptide identification from metaproteomics data.
Date: July 8, 2021
Creator: Feng, Shichao; Sterzenbach, Ryan & Guo, Xuan
Partner: UNT College of Engineering
open access

Metabolic Syndrome, Inflammation, and Cancer

Description: Article introducing a special issue discussing the link between the metabolic syndrome and the development and progression of cancer. The role of inflammation in these diseases and identification of new therapeutic targets are of great significance. This special issue contributes original research papers and review articles that motivate the continuous efforts to comprehend the mechanisms, production, and management related to cancers associated with the metabolic syndrome.
Date: July 6, 2017
Creator: Wu, Yong; Dong, Yunzhou; Duan, Shengzhong; Zhu, Donghui & Deng, Lin
Partner: UNT College of Engineering
open access

Flexible and Stretchable Bioelectronics

Description: Article reviewing several several flexible and stretchable materials used as substrate, stretchable electrical conduits and encapsulation, design modifications for stretchability, fabrication techniques, methods of signal transmission and monitoring, and the power sources for these stretchable bioelectronics. Ultimately, these bioelectronic devices can be used for wide range of applications from skin bioelectronics and biosensing devices, to neural implants for diagnostic or therapeutic purpose… more
Date: February 23, 2022
Creator: Chitrakar, Chandani; Hedrick, Eric; Adegoke, Lauren & Ecker, Melanie
Partner: UNT College of Engineering
open access

Accelerometer-Based Automated Counting of Ten Exercises without Exercise-Specific Training or Tuning

Description: Article presents research that creates an automatic repetition counting system that is flexible enough to measure multiple distinct and repeating movements during physical therapy without being trained on the specific motion.
Date: October 10, 2020
Creator: Zelman, Samuel; Dow, Michael; Tabashum, Thasina; Xiao, Ting & Albert, Mark
Partner: UNT College of Engineering
open access

Using a microprocessor knee (C-Leg) with appropriate foot transitioned individuals with dysvascular transfemoral amputations to higher performance levels: a longitudinal randomized clinical trial

Description: Article evaluating whether advanced prostheses can provide better safety and performance capabilities to maintain and improve quality of life in individuals who are predominantly designated MFCL level K2. This study used a 13 month longitudinal clinical trial to determine the benefits of using a C-Leg and 1M10 foot in individuals at K2 level with transfemoral amputation due to vascular disease.
Date: May 25, 2021
Creator: Jayaraman, Chandrasekaran; Mummidisetty, Chaithanya K.; Albert, Mark; Lipschutz, Robert; Hoppe-Ludwig, Shenan; Mathur, Gayatri et al.
Partner: UNT College of Engineering
open access

A Dense Stereovision System for 3D Body Imaging

Description: Article presents a 3D body imaging system built upon stereovision technology which utilizes paired, high-resolution single-lens reflex (SLR) cameras to image the front and back body surfaces of a person, and robust and efficient stereo matching algorithms to reconstruct the 3D surface of the body with high-density data clouds.
Date: November 26, 2019
Creator: Yao, Ming & Xu, Bugao
Partner: UNT College of Engineering
open access

Preface: International Conference on Recent Advancements in Biomedical Engineering - 2021

Description: This article showcasing the editorial team welcomes all readers to the proceedings of International Conference on Recent Advancements in Biomedical Engineering (ICRABE-2021). The conference was inspired by the fusion of science and engineering principles in healthcare services and products. The conference aims to initiate exchange of innovative ideas between students, research scholar and faculties. Specifically, mechanical principles, power control for medical devices, nanomaterials and associ… more
Date: 2021
Creator: International Conference on Recent Advancements in Biomedical Engineering
Partner: UNT College of Engineering
open access

The Effect of Magnesium Deficiency on Neurological Disorders: A Narrative Review Article

Description: This article critically discusses the role of Magnesium by reviewing recent literature and available data concerning the role of magnesium in neurological disorders. The authors summarize the role of Mg in neurological disorders to illustrate the symptoms caused by Mg-deficiency and the possible underlying mechanisms.
Date: March 2019
Creator: Xue, Wenwen; You, Jing; Su, Yingchao & Wang, Qinglu
Partner: UNT College of Engineering
open access

Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis

Description: This article is a review that illustrates the involvement of MMP-13 in the initiation and progression of Osteoarthritis (OA) through the regulation of MMP-13 activity at the molecular and epigenetic levels, as well as the strategies that have been employed against MMP-13. The aim of this review is to identify MMP-13 as an attractive target for inhibitor development in the treatment of OA.
Date: February 9, 2021
Creator: Hu, Qichan & Ecker, Melanie
Partner: UNT College of Engineering
open access

Bioengineering Systems for Modulating Notch Signaling in Cardiovascular Development, Disease, and Regeneration

Description: This article is a review summarizing the significant roles of Notch signaling in individual cardiac cell types. It covers the bioengineering systems of microfluidics, hydrogel, spheroid, and 3D bioprinting and provides insights into ancillary supports of bioengineering systems, varied types of cardiovascular cells, and advanced characterization approaches in further refining Notch signaling in cardiovascular development, disease, and regeneration.
Date: September 30, 2021
Creator: Huerta Gomez, Angello; Joshi, Sanika; Yang, Yong; Tune, Johnathan D. & Zhao, Ming-Tao
Partner: University of North Texas
open access

Potential Toxicity and Underlying Mechanisms Associated with Pulmonary Exposure to Iron Oxide Nanoparticles: Conflicting Literature and Unclear Risk

Description: This review article will focus on known risks following iron oxide nanoparticles (IONPs) exposure supported by human, animal, and cell culture-based studies, the potential challenges intrinsic to IONPs toxicity assessment, and how these may contribute to the poorly characterized IONPs toxicity profile.
Date: October 6, 2017
Creator: Kornberg, Tiffany G.; Stueckle, Todd A.; Antonini, James M.; Rojanasakul, Liying W.; Castranova, Vincent; Yang, Yong et al.
Partner: UNT College of Engineering
open access

Wearable airbag technology and machine learned models to mitigate falls after stroke

Description: Article discusses wearable airbag technology that has been designed to detect and mitigate fall impact. However, this technology has not been validated for the stroke population, so authors investigated whether population-specific training data and modeling parameters are required to pre-detect falls in a chronic stroke population.
Date: June 17, 2022
Creator: Botonis, Olivia K.; Harari, Yaar; Embry, Kyle R.; Mummidisetty, Chaithanya K.; Riopelle, David; Giffhorn, Matt et al.
Partner: UNT College of Engineering
open access

Unsupervised learning in images and audio to produce neural receptive fields: a primer and accessible notebook

Description: This article presents a consolidated review of Independent Component Analysis (ICA) as an efficient neural coding scheme with the ability to model early visual and auditory neural processing.
Date: October 19, 2021
Creator: Urs, Namratha; Behpour, Sahar; Georgaras, Angie & Albert, Mark
Partner: University of North Texas
open access

Harnessing nanofiber alignment and pore size to promote stem cell self-renewal and differentiation

Description: Article describes how stem cell therapy holds immense potential for regenerative medicine, but its applications are limited due to the loss of pluripotency during in vitro expansion. This study reveals that the arrangement of electrospun fibers aligns with the distribution and strength of the electric field through both experimentation and simulation.
Date: July 25, 2023
Creator: Wei, Qiang; Blake, Laurence; Liu, Jiafeng; Man, Kun; Liang, Cindy; Teoh, Alexandra et al.
Partner: UNT College of Engineering
open access

Pathological Targets for Treating Temporal Lobe Epilepsy: Discoveries From Microscale to Macroscale

Description: This review article summarizes the latest neuropathological discoveries at the molecular, cellular, and tissue levels involving both animal and patient studies, aiming to explore epileptogenesis and highlight new potential targets in the diagnosis and treatment of temporal lobe epilepsy (TLE).
Date: January 7, 2022
Creator: You, Jing; Huang, Haiyan; Chan, Clement T. Y. & Li, Lin
Partner: UNT College of Engineering
open access

A Review of Rehabilitative and Assistive Technologies for Upper-Body Exoskeletal Devices

Description: Authors state that this journal review article focuses on the use of assistive and rehabilitative exoskeletons as a new opportunity for individuals with diminished mobility. Overall, this article serves as a valuable resource for individuals working in the field of assistive and rehabilitative exoskeletons, providing insight into the state of the art and potential areas for improvement.
Date: April 20, 2023
Creator: Hays, Emilly; Slayton, Jack; Tejeda-Godinez, Gary; Carney, Emily; Cruz, Kobe; Exley, Trevor et al.
Partner: UNT College of Engineering
open access

Modulating 3D Cellular Connectivity Via Spatially-Controlled Programmable Bonding

Description: Data management plan for the grant "Modulating 3D Cellular Connectivity Via Spatially-Controlled Programmable Bonding." This project seeks to demonstrate proof-of-concept for technology that allows one to systematically place cells on substrates to create complex 3D assemblies with precise control over individual cellular interactions. The technology generated within this proposal will open new avenues for studying multicellular communication pathways, stem cell differentiation, and understandi… more
Date: 2021-09-01/2023-08-31
Creator: Meckes, Brian
Partner: UNT College of Engineering
open access

Development of Genetic Sensors and Circuits for Creating Novel Cellular Behaviors

Description: Data management plan for the grant "Development of Genetic Sensors and Circuits for Creating Novel Cellular Behaviors." This research is expected to advance the capability to engineer organisms for biomedical uses. Specifically, the outcomes of this project include design principles for engineering regulators from different protein families, an extensive set of genetic sensors for detecting a broad range of signals, and novel genetic circuits that address uprising problems in biomedical fields.… more
Date: 2021-09-15/2026-08-31
Creator: Chan, Clement T. Y.
Partner: UNT College of Engineering
open access

PP2Cδ inhibits p300-mediated p53 acetylation via ATM/BRCA1 pathway to impede DNA damage response in breast cancer

Description: Article describes study which indicates that nuclear type 2C protein phosphatase (PP2Cδ) impairs p53 acetylation and DNA damage response by compromising BRCA1 function in breast cancer development.
Date: October 16, 2019
Creator: Li, Qun; Hao, Qiongyu; Cao, Wei; Li, Jieqing; Wu, Ke; Elshimali, Yahya et al.
Partner: UNT College of Engineering
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