Analysis of Gene Targeting & Nonhomologous End-joining. Final Report
Description:
Overall, we identified a number of new proteins that participate in nonhomologous end-joining and also in telomere addition to the ends of broken chromosomes. We showed that NHEJ is severely reduced in cells expressing both yeast mating-type genes and then went on to identify the NEJ1 gene that was under this control. We showed the epistasis relations among a set of mutations that impair telomere addition and we showed that there are in fact two pathways to repair broken chromosomes in the abse…
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Date:
November 30, 2002
Creator:
Haber, J. E.
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Partner:
UNT Libraries Government Documents Department