CANCELLED EMT and back again: does cellular plasticity fuel neoplastic progression?
Description:
Epithelial-mesenchymal transition (EMT) is a cellular transdifferentiation program that facilitates organ morphogenesis and tissue remodeling in physiological processes such as embryonic development and wound healing. However, a similar phenotypic conversion is also detected in fibrotic diseases and neoplasia, in which it is associated with disease progression. EMT in cancer epithelial cells often appears to be an incomplete and bi-directional process. Here we discuss the phenomenon of EMT as i…
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Date:
February 24, 2007
Creator:
Turley, Eva A.; Veiseh, Mandana; Radisky, Derek C. & Bissell, MinaJ.
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UNT Libraries Government Documents Department