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Antibiotic Resistance: Federal Agencies Need to Better Focus Efforts to Address Risk to Humans from Antibiotic Use in Animals

Description: A letter report issued by the General Accounting Office with an abstract that begins "Antibiotic resistance is a growing public health concern; antibiotics used in animals raised for human consumption contributes to this problem. Three federal agencies address this issue--the Department of Health and Human Services' (HHS) Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC), and the Department of Agriculture (USDA). GAO examined (1) scientific evidence on the … more
Date: April 22, 2004
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
open access

Information on Selected Personnel Practices at the Justice Department

Description: Correspondence issued by the General Accounting Office with an abstract that begins "This letter responds to a request that we provide information on selected personnel practices at the Justice Department. On March 1, 2004, we briefed Congress on the results of our review. This letter transmits information provided during that briefing. Specifically, the slides enclosed in this letter describe (1) Justice's hiring processes for entry-level and lateral (i.e., experienced) career attorneys, (2) t… more
Date: April 22, 2004
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
open access

Fiscal Year 2005 Budget Request: U.S. General Accounting Office

Description: Testimony issued by the General Accounting Office with an abstract that begins "GAO exists to support the Congress in meeting its constitutional responsibilities and to help improve the performance and ensure the accountability of the federal government for the benefit of the American people. In the years ahead, its support to the Congress will likely prove even more critical because of the pressures created by the nation's large and growing long-term fiscal imbalance, which is driven primarily… more
Date: April 22, 2004
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
open access

Continuity of Operations: Improved Planning Needed to Ensure Delivery of Essential Services

Description: Testimony issued by the General Accounting Office with an abstract that begins "To ensure that essential government services are available in emergencies--such as terrorist attacks, severe weather, or building-level emergencies--federal agencies are required to develop continuity of operations (COOP) plans. Responsibility for formulating guidance on these plans and for assessing executive branch COOP capabilities lies with the Federal Emergency Management Agency (FEMA), under the Department of … more
Date: April 22, 2004
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
open access

Aviation Security: Private Screening Contractors Have Little Flexibility to Implement Innovative Approaches

Description: Testimony issued by the General Accounting Office with an abstract that begins "The terrorist attacks of September 11, 2001, resulted in fundamental changes in the way the United States screens airport passengers and their property. One of the most significant changes was the shift from using private screeners to using federal screeners at all but five commercial airports in the United States. These five airports are part of a pilot program, where private screeners perform screening functions. … more
Date: April 22, 2004
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
open access

Resolving the Nature of the LMC Microlensing Event LMC-5

Description: The authors present the results from an analysis of Hubble Space Telescope High Resolution Camera data for the Large Magellanic Cloud microlensing event MACHO-LMC-5. By determining the parallax and proper motion of this object they find that the lens is an M dwarf star at a distance of 578{sub -53}{sup +65}pc with a proper motion of 21.39 {+-} 0.04 mas/yr. Based on the kinematics and location of this star is it more likely to be part of the Galactic thick disk than thin disk population. They co… more
Date: April 22, 2004
Creator: Drake, A J; Cook, K H & Keller, S C
Partner: UNT Libraries Government Documents Department
open access

Evaluation Of Microdosing Strategies For Studies In Preclinical Drug Development: Demonstration Of Linear Pharmacokinetics In Dogs Of A Nucleoside Analogue Over A 50-Fold Dose Range

Description: The technique of accelerator mass spectrometry (AMS) was validated successfully and utilized to study the pharmacokinetics and disposition in dogs of a preclinical drug candidate (Compound A), after oral and intravenous administration. The primary objective of this study was to examine whether Compound A displayed linear kinetics across sub-pharmacological (microdose) and pharmacological dose ranges in an animal model, prior to initiation of a human microdose study. The AMS-derived disposition … more
Date: April 22, 2004
Creator: Sandhu, P; Vogel, J S; Rose, M J; Ubick, E A; Brunner, J E; Wallace, M A et al.
Partner: UNT Libraries Government Documents Department
open access

Little Supersymmetry and the Supersymmetric Little Hierarchy Problem

Description: The current experimental lower bound on the Higgs mass significantly restricts the allowed parameter space in most realistic supersymmetric models, with the consequence that these models exhibit significant fine-tuning. We propose a solution to this `supersymmetric little hierarchy problem'. We consider scenarios where the stop masses are relatively heavy - in the 500 GeV to a TeV range. Radiative stability of the Higgs soft mass against quantum corrections from the top quark Yukawa coupling is… more
Date: April 22, 2004
Creator: Birkedal, Andreas; Chacko, Z. & Gaillard, Mary K.
Partner: UNT Libraries Government Documents Department
open access

Design of a 2 Slot VLPC Cryostat Cooled by a Cryocooler

Description: The conceptual design and preliminary engineering calculations have been completed for a two cassette cryostat. This report summarizes the design. A cryocooler is permanently mounted in the center of a stainless steel, 0.75 inch thick top lid. The cryocooler sits upon a spacer which raises the cooling stage elevations to favorably match the cassette heat intercept elevations. The top lid (32.0-inch outside diameter) mates to a 24-inch pipe size flange with o-ring. The 24-inch pipe size vacuum v… more
Date: April 22, 2004
Creator: Rucinski, Russell A.
Partner: UNT Libraries Government Documents Department
open access

EMSP Project 70070: Reactivity of Primary Soil Minerals and Secondary Precipitates Beneath Leaking Hanford Waste Tanks - Final Report

Description: Since the late 1950s, leaks from 67 single-shell tanks at the Hanford Site have released about 1 million curies to the underlying sediments. The radioactive material was contained in water-based solutions generally characterized as having high pH values (basic solutions), high nitrate and nitrite concentrations, and high aluminum concentrations. The solutions were also hot, in some cases at or near boiling, as well as complex and highly variable in composition reflecting solutions obtained from… more
Date: April 22, 2004
Creator: Nagy, Kathryn L.
Partner: UNT Libraries Government Documents Department
open access

Statistical Tools for Forensic Analysis of Toolmarks

Description: Recovery and comparison of toolmarks, footprint impressions, and fractured surfaces connected to a crime scene are of great importance in forensic science. The purpose of this project is to provide statistical tools for the validation of the proposition that particular manufacturing processes produce marks on the work-product (or tool) that are substantially different from tool to tool. The approach to validation involves the collection of digital images of toolmarks produced by various tool ma… more
Date: April 22, 2004
Creator: Baldwin, David; Morris, Max; Bajic, Stan; Zhou, Zhigang & Kreiser, James
Partner: UNT Libraries Government Documents Department
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Determination of Sulfur in High-Level Waste Sludge by Inductively Coupled Plasma-Atomic Emission Spectroscopy and Ion Chromatography

Description: Significant differences (approximately 30 percent) have been observed in the sulfur measurements in high-level waste sludge by the Analytical Development Section (ADS) using the inductively coupled plasma-atomic emission spectroscopy (ICP-AES) method compared with the ADS ion chromatography (IC) method. Since the measured concentrations of sulfur in the sludge approached the maximum concentration that can be processed in the DWPF, experiments were performed to determine the source of the differ… more
Date: April 22, 2004
Creator: COLEMAN, CJ
Partner: UNT Libraries Government Documents Department
open access

Soil carbon changes for bioenergy crops.

Description: Bioenergy crops, which displace fossil fuels when used to produce ethanol, biobased products, and/or electricity, have the potential to further reduce atmospheric carbon levels by building up soil carbon levels, especially when planted on lands where these levels have been reduced by intensive tillage. The purpose of this study is to improve the characterization of the soil carbon (C) sequestration for bioenergy crops (switchgrass, poplars, and willows) in the Greenhouse gases, Regulated Emissi… more
Date: April 22, 2004
Creator: Andress, D.
Partner: UNT Libraries Government Documents Department
open access

Using an Active Pixel Sensor In A Vertex Detector

Description: Research has shown that Active Pixel CMOS sensors can detect charged particles. We have been studying whether this process can be used in a collider environment. In particular, we studied the effect of radiation with 55 MeV protons. These results show that a fluence of about 2 x 10{sup 12} protons/cm{sup 2} reduces the signal by a factor of two while the noise increases by 25%. A measurement 6 months after exposure shows that the silicon lattice naturally repairs itself. Heating the silicon to … more
Date: April 22, 2004
Creator: Matis, Howard S.; Bieser, Fred; Chen, Yandong; Gareus, Robin; Kleinfelder, Stuart; Oldenburg, Markus et al.
Partner: UNT Libraries Government Documents Department
open access

Final Report-DE FG02 92ER20061

Description: A dosage analysis of gene expression was conducted using aneuploids of maize. The findings of this project led to the concept that regulatory genes in higher eukaryotes has mostly dosage dependent and are the underlying basis of quantitative traits and aneuploid syndromes.
Date: April 22, 2004
Creator: Birchler, James A.
Partner: UNT Libraries Government Documents Department
open access

Growth of nanocrystalline MoO3 on Au(111) studied by in-situ STM

Description: The growth of nanocrystalline MoO{sub 3} islands on Au(111) using physical vapor deposition of Mo has been studied by scanning tunneling microscopy (STM) and low energy electron diffraction (LEED). The growth conditions affect the shape and distribution of the MoO{sub 3} nanostructures, providing a means of preparing materials with different percentages of edge sites that may have different chemical and physical properties than atoms in the interior of the nanostructures. MoO{sub 3} islands wer… more
Date: April 22, 2004
Creator: Biener, M M; Biener, J; Schalek, R & Friend, C M
Partner: UNT Libraries Government Documents Department
open access

Validation of Stress Corrosion Cracking Model for High Level Radioactive-Waste Packages

Description: A stress corrosion cracking (SCC) model has been adapted for performance prediction of high level radioactive-waste packages to be emplaced in the proposed Yucca Mountain radioactive-waste repository. SCC is one form of environmentally assisted cracking resulting from the presence of three factors: metallurgical susceptibility, critical environment, and tensile stresses. For waste packages of the proposed Yucca Mountain repository, the outer barrier material is the highly corrosion-resistant Al… more
Date: April 22, 2004
Creator: Lu, S; Gordon, G & Andresen, P
Partner: UNT Libraries Government Documents Department
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Study of the Reactions Controlling the Mobility of Uranium in Ground and Surface Water Systems in Contact with Apatite

Description: The objective of this project was to define the mechanisms, equilibria, kinetics, and extent of sorption of aqueous uranium onto hydroxyapatite (Ca{sub 5}(PO{sub 4}){sub 3}(OH)) for a range of pH, ionic strength, aqueous uranium concentration, dissolved carbon/air CO{sub 2}, and mineral surface area. We conducted chemical modeling, batch and flow-through experiments, chemical analysis, x-ray absorption and diffraction measurement, and electron microscopy. Our motivation was the need to immobili… more
Date: April 22, 2004
Creator: Taffet, M
Partner: UNT Libraries Government Documents Department
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Mars Ascent Propulsion Trades with Trajectory Analysis

Description: Optimized trajectories to a 500 km circular orbit are calculated for vehicles having a 100 kg Mars launch mass. Staging trades, thrust optimization, and the importance of vehicle shape for drag are all taken into consideration. The high acceleration of solid rockets requires a steep trajectory for drag avoidance, followed by a relatively large circularization burn, appropriate for a second stage. Liquid thrust reduces drag, resulting in less steep trajectories which have small circularization b… more
Date: April 22, 2004
Creator: Whitehead, J
Partner: UNT Libraries Government Documents Department
open access

Grant No DE-FG02-03ER83720 Report for US Department of Engery

Description: Effective and reliable nuclear monitoring requires discrimination between small magnitude explosions and earthquakes based on the use of limited regional data. Lg is generally the largest seismic phase from both explosion and earthquake sources recorded at regional distances. For small events, Lg may sometimes be the only well-recorded seismic phase so that discriminants based only on the use of Lg are especially desirable. Recent research has provided significantly better understanding of Lg b… more
Date: April 22, 2004
Creator: Chan, Winston & Wagner, Robert
Partner: UNT Libraries Government Documents Department
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