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Pediatric Drug Research: Studies Conducted under Best Pharmaceuticals for Children Act

Description: A letter report issued by the Government Accountability Office with an abstract that begins "About two-thirds of drugs that are prescribed for children have not been studied and labeled for pediatric use, which places children at risk of being exposed to ineffective treatment or incorrect dosing. The Best Pharmaceuticals for Children Act (BPCA), enacted in 2002, encourages the manufacturers, or sponsors, of drugs that still have marketing exclusivity--that is, are on-patent--to conduct pediatri… more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Social Security Reform: Greater Transparency Needed about Potential General Revenue Financing

Description: A letter report issued by the Government Accountability Office with an abstract that begins "Absent reform, Social Security's financing gap will grow until currently scheduled benefits can no longer be paid in full. Recent reform proposals often include general revenue (GR)--a major change that can have significant implications for the budget as a whole. This report addresses these issues: (1) What information is available about GR in recent proposal scorings by Social Security's Office of the … more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Federal Aviation Administration: Key Issues in Ensuring the Efficient Development and Safe Operation of the Next Generation Air Transportation System

Description: Testimony issued by the Government Accountability Office with an abstract that begins "The Federal Aviation Administration (FAA) operates one of the safest air transportation systems in the world. It is, however, a system under strain. The skies are becoming more crowded every day, with an estimated 1 billion passengers per year expected by 2015. The current aviation system cannot be expanded to meet this growth. The reauthorization of FAA is an opportunity to examine how the agency is managing… more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
open access

Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning

Description: A letter report issued by the Government Accountability Office with an abstract that begins "Following the invasion of Iraq in March 2003--known as Operation Iraqi Freedom (OIF)--concerns were raised about how the Department of Defense (DOD) secured Iraqi conventional munitions storage sites during and after major combat operations. Because of the broad interest in this issue, GAO conducted this work under the Comptroller General's authority to conduct evaluations. This report examines (1) the … more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Next Generation Air Transportation System: Progress and Challenges in Planning and Implementing the Transformation of the National Airspace System

Description: Testimony issued by the Government Accountability Office with an abstract that begins "The skies over America are becoming more crowded every day. The consensus of opinion is that the current aviation system cannot be expanded to meet this projected growth. Recognizing the need for system transformation, in 2003 Congress authorized the Joint Planning and Development Office (JPDO) and requires the office to operate in conjunction with multiple federal agencies, including the Departments of Trans… more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
open access

Operation Iraqi Freedom: DOD Should Apply Lessons Learned Concerning the Need for Security over Conventional Munitions Storage Sites to Future Operations Planning

Description: Testimony issued by the Government Accountability Office with an abstract that begins "GAO is releasing a report today on lessons learned concerning the need for security over conventional munitions storage sites which provides the basis for this testimony. Following the invasion of Iraq in March 2003--known as Operation Iraqi Freedom (OIF)--concerns were raised about how the Department of Defense (DOD) secured Iraqi conventional munitions storage sites during and after major combat operations.… more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
open access

Defense Acquisitions: Analysis of Costs for the Joint Strike Fighter Engine Program

Description: Testimony issued by the Government Accountability Office with an abstract that begins "The Joint Strike Fighter (JSF) is the linchpin of future Department of Defense (DOD) tactical aircraft modernization efforts because of the sheer size of the program and its envisioned role as the replacement for hundreds of aircraft that perform a wide variety of missions in the Air Force, Navy, and Marine Corps. DOD implemented the JSF alternate engine development program in 1996 to provide competition betw… more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
open access

Stabilizing Iraq: Preliminary Observations on Budget and Management Challenges of Iraq's Security Ministries

Description: Testimony issued by the Government Accountability Office with an abstract that begins "In November 2005, the President issued the National Strategy for Victory in Iraq. According to the strategy, victory will be achieved when Iraq is peaceful, united, stable, secure, well integrated into the international community, and a full partner in the global war on terror. To help Iraq achieve this, the U.S. is, among other efforts, helping strengthen the capabilities of the Iraq Ministries of Defense an… more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
open access

FINAL ANALYTICAL RESULTS FROM THE EXAMINATION OF CORROSION ON SECTIONS OF CORROSION PROBE REMOVED FROM TANK 241-AN-107 ON 08/10/2006

Description: Tank Farms Operations removed an electrochemical noise probe from Tank 241-AN-107. In the field, the probe was cut into four sections, wrapped, and placed in a 55-gallon drum, This drum was delivered to the 222-S Laboratory. The 222 S Laboratory unpackaged the sections of the AN-107 electrochemical noise probe and examined the material for evidence of corrosion. Each of the four sections contained three C-ring and three bullet specimens. The specimens were examined for pitting corrosion, crevic… more
Date: March 22, 2007
Creator: JB, DUNCAN & GA, COOKE
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Development of a Cell-Based Fluorescence Resonance Energy Transfer Reporter for Bacillus anthracis Lethal Factor Protease

Description: We report the construction of a cell-based fluorescent reporter for anthrax lethal factor (LF) protease activity using the principle of fluorescence resonance energy transfer (FRET). This was accomplished by engineering an Escherichia coli cell line to express a genetically encoded FRET reporter and LF protease. Both proteins were encoded in two different expression plasmids under the control of different tightly controlled inducible promoters. The FRET-based reporter was designed to contain a … more
Date: March 22, 2007
Creator: Kimura, R H; Steenblock, E R & Camarero, J A
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Proposal for Extending the UPC Memory Copy Library Functions andSupporting Extensions to GASNet, Version 2.0

Description: This document outlines a proposal for extending UPC'spoint-to-point memcpy library with support for explicitly non-blockingtransfers, and non-contiguous (indexed and strided) transfers. Variousportions of this proposal could stand alone as independent extensions tothe UPC library. The designs presented here are heavily influenced byanalogous functionality which exists in other parallel communicationsystems, such as MPI, ARMCI, Titanium, and network hardware API's such asQuadrics elan, Infiniban… more
Date: March 22, 2007
Creator: Bonachea, Dan
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

K Basins Groundwater Monitoring Task, K Basins Closure Project: Report for October, November, and December 2006

Description: This report provides information on groundwater monitoring at the K Basins during October, November, and December 2006. Conditions remained very similar to those reported in the previous quarterly report, with no evidence in monitoring results to suggest groundwater impact from current loss of basin water to the ground. The K Basins monitoring network will be modified in the coming months as a consequence of new wells having been installed near KW Basin as part of a pump-and-treat system for ch… more
Date: March 22, 2007
Creator: Peterson, Robert E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

FULL-SCALE TREATMENT WETLANDS FOR METAL REMOVAL FROM INDUSTRIAL WASTEWATER

Description: The A-01 NPDES outfall at the Savannah River Site receives process wastewater discharges and stormwater runoff from the Savannah River National Laboratory. Routine monitoring indicated that copper concentrations were regularly higher than discharge permit limit, and water routinely failed toxicity tests. These conditions necessitated treatment of nearly one million gallons of water per day plus storm runoff. Washington Savannah River Company personnel explored options to bring process and runof… more
Date: March 22, 2007
Creator: Nelson, E & John Gladden, J
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Drug Safety: FDA Needs to Further Address Shortcomings in Its Postmarket Decision-making Process

Description: Testimony issued by the Government Accountability Office with an abstract that begins "GAO was asked to testify on the effectiveness of the Food and Drug Administration's (FDA) postmarket decision-making process. This testimony is based on Drug Safety: Improvement Needed in FDA's Postmarket Decision-making and Oversight Process, GAO-06-402 (March 31, 2006). The report focused on the complex interaction between two offices within FDA that are involved in postmarket drug safety activities: the Of… more
Date: March 22, 2007
Creator: United States. Government Accountability Office.
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
open access

Dose, exposure time, and resolution in Serial X-ray Crystallography

Description: Using detailed simulation and analytical models, the exposure time is estimated for serial crystallography, where hydrated laser-aligned proteins are sprayed across a continuous synchrotron beam. The resolution of X-ray diffraction microscopy is limited by the maximum dose that can be delivered prior to sample damage. In the proposed Serial Crystallography method, the damage problem is addressed by distributing the total dose over many identical hydrated macromolecules running continuously in a… more
Date: March 22, 2007
Creator: Starodub, D.; Rez, P.; Hembree, G.; Howells, M.; Shapiro, D.; Chapman, H. N. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Tri-Laboratory Linux Capacity Cluster 2007 SOW

Description: The Advanced Simulation and Computing (ASC) Program (formerly know as Accelerated Strategic Computing Initiative, ASCI) has led the world in capability computing for the last ten years. Capability computing is defined as a world-class platform (in the Top10 of the Top500.org list) with scientific simulations running at scale on the platform. Example systems are ASCI Red, Blue-Pacific, Blue-Mountain, White, Q, RedStorm, and Purple. ASC applications have scaled to multiple thousands of CPUs and a… more
Date: March 22, 2007
Creator: Seager, M
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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