Breast cancer by proxy: Can the microenvironment be both the cause and consequence?
Description:
Breast cancer is one of the most clear-cut examples of a solid tumor in which systemic cues play a decisive part in its development. The breast tissue is constantly subjected to changes in hormone levels and modifications in the microenvironment. This scenario is even more striking during tumor development because of the dramatic loss or aberration of basement membrane (BM) and myoepithelial cells and the gain of peritumoral myofibroblasts. We suggest that the microenvironment, defined here as …
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Date:
November 16, 2008
Creator:
Ronnov-Jessen, Lone & Bissell, Mina J
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UNT Libraries Government Documents Department