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Chemical and Genetic Studies on the Formation of Pyrrolones During the Biosynthesis of Cytochalasans

Description: This article investigates the role of the highly conserved α,β-hydrolase enzymes PyiE and ORFZ during the biosynthesis of pyrichalasin H and the ACE1 metabolite, respectively, using gene knockout and complementation techniques. Taken together the results suggest that the α,β-hydrolase enzymes are essential for first ring cyclisation, but the precise nature of the intermediates remains to be determined.
Date: November 4, 2020
Creator: Zhang, Haili; Hantke, Verena; Bruhnke, Pia; Skellam, Elizabeth & Cox, Russell J.
Item Type: Refine your search to only Article
Partner: UNT College of Science
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Alumni Spotlight #6: Creating Progress in a World of Change with Dean Lindsay

Description: Podcast produced by the Osher Lifelong Learning Institute (OLLI) that features an interview with UNT Alumnus Dean Lindsay, business author and keynote speaker. Susan and Dean discuss the ideas he brings to the table as a keynote speaker for high class clientele, and how these ideas can be applied to the everyday person coping with the COVID-19 pandemic. They also discuss his accomplishments in the acting and music fields.
Date: November 4, 2020
Duration: 37 minutes 53 seconds
Creator: University of North Texas. Osher Lifelong Learning Institute.
Item Type: Refine your search to only Sound
Partner: UNT Libraries Special Collections
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