Measurement of the Second Order Non-linear Susceptibility of Collagen using Polarization Modulation and Phase-sensitive Detection
Description:
The measurement of the second order nonlinear susceptibility of collagen in various biological tissues has potential applications in the detection of structural changes which are related to different pathological conditions. We investigate second harmonic generation in rat-tail tendon, a highly organized collagen structure consisting of parallel fibers. Using an electro-optic modulator and a quarter-wave plate, we modulate the linear polarization of an ultra-short pulse laser beam that is used …
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Date:
March 3, 2001
Creator:
Stoller, P.; Kim, B. M.; Rubenchik, A. M.; Reiser, K. M. & Da Silva, L. B.
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