Benchmarking Metagenomic Classifiers on Simulated Ancient and Modern Metagenomic Data
Description:
Article describes how taxonomic profiling of ancient metagenomic samples is challenging due to the accumulation of specific damage patterns on DNA over time. The authors performed a comprehensive evaluation on simulated metagenomes representing human dental calculus microbiome, with the level of DNA damage successively raised to mimic modern to ancient metagenomes.
Date:
October 2, 2023
Creator:
Pusadkar, Vaidehi & Azad, Rajeev K.
Item Type:
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Partner:
UNT College of Science