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Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

Description: Subclassification of ovarian carcinomas can be used to guide treatment and determine prognosis. Germline and somatic mutations, loss of heterozygosity (LOH), and epigenetic events such as promoter hypermethylation can lead to decreased expression of BRCA1/2 in ovarian cancers. The mechanism of BRCA1/2 loss is a potential method of subclassifying high grade serous carcinomas. A consecutive series of 49 ovarian cancers was assessed for mutations status of BRCA1 and BRCA2, LOH at the BRCA1 and BRC… more
Date: May 2, 2008
Creator: Gilks, C. Blake; Press, Joshua Z.; De Luca, Alessandro; Boyd, Niki; Young, Sean; Troussard, Armelle et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Effect of Casting Conditions and Composition on Microstructural Gradients in Roll Cast Aluminum Alloys

Description: Twin Roll Casting (TRC) is a process by which thin strip is produced directly from molten metal. This process has many advantages over traditional Direct Chill (DC) casting where metal is cast into large slabs or ingots and subsequently hot and cold rolled into strips. While the DC casting involves large capital investment and energy consumption, TRC produces strip with thickness in the range of 10 mm to 2.5 mm in one operation without hot rolling, with less cost, energy usage and equipment req… more
Date: May 2, 2008
Creator: Patterson, Burton R.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Electron-Heated Target Temperature Measurements in Petawatt Laser Experiments Based on Extreme Ultraviolet Imaging and Spectroscopy

Description: Three independent methods (XUV spectroscopy, imaging at 68 eV and 256 eV) have been used to measure planar target rear surface plasma temperature due to heating by hot electrons. The hot electrons are produced by ultra-intense laser plasma interactions using the 150 J, 0.5 ps Titan laser. Soft x-ray spectroscopy in the 50-400 eV region and imaging at the 68 eV and 256 eV photon energies were used to determine the rear surface temperature of planar CD targets. Temperatures were found to be in th… more
Date: May 2, 2008
Creator: Ma, T. A.; Beg, F. N.; Macphee, A. G.; Chung, H. K.; Key, M. H.; Mackinnon, A. J. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

A Bremsstrahlung Spectrometer using k-edge and Differential Filters with Image plate dosimeters

Description: A Bremsstrahlung spectrometer using k-edge and differential filtering has been used with Image Plate dosimeters to measure the x-ray fluence from short-pulse laser/target interactions. An electron spectrometer in front of the Bremsstrahlung spectrometer deflects electrons from the x-ray line of sight and simultaneously measures the electron spectrum. The response functions were modeled with the Monte Carlo code Integrated Tiger Series 3.0 and the dosimeters calibrated with radioactive sources. … more
Date: May 2, 2008
Creator: Chen, C.; Mackinnon, A.; Beg, F.; Chen, H.; Key, M.; King, J. A. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Influence of radiation damage and isochronal annealing on the magnetic susceptibility of Pu(1-x)Am(x) alloys

Description: Results of radiation damage in Pu and Pu{sub 1-x}Am{sub x} alloys studied with magnetic susceptibility, {chi}(T), and resistivity are presented. Damage accumulated at low temperatures increases {chi}(T) for all measured alloys, with the trend generally enhanced as the lattice expands. There is a trend towards saturation observable in the damage induced magnetic susceptibility data, that is not evident in similar damage induced resistivity data taken on the same specimen. A comparison of isochro… more
Date: May 2, 2008
Creator: McCall, S; Fluss, M; Chung, B & Haire, R
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Overview of equilibrium reconstruction on DIII-D using new measurements from an expanded motional Stark effect diagnostic

Description: Motional Stark effect (MSE) measurements constrain equilibrium reconstruction of DIII-D tokamak plasmas using the equilibrium code EFIT. In 2007, two new MSE arrays were brought online, bringing the system to three core arrays, two edge arrays, and 64 total channels. We present the first EFIT reconstructions using this expanded system. Safety factor and E{sub R} profiles produced by fitting to data from the two new arrays and one of the other three agree well with independent measurements. Comp… more
Date: May 2, 2008
Creator: Holcomb, C; Makowski, M; Allen, S; Meyer, W & Van Zeeland, M
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Angular Distributions in the Decays B to K*l+l-

Description: The authors use a sample of 384 million B{bar B} events collected with the BABAR detector at the PEP-II e{sup +}e{sup -} collider to study angular distributions in the rare decays B {yields} K*{ell}{sup +}{ell}{sup -}, where {ell}{sup +}{ell}{sup -} is either e{sup +}e{sup -} or {mu}{sup +}{mu}{sup -}. For low dilepton invariant masses, m{sub {ell}{ell}} < 2.5 GeV/c{sup 2}, they measure a lepton forward-backward asymmetry {Alpha}{sub FB} = 0.24{sub -0.23}{sup +0.18} {+-} 0.05 and K* longitud… more
Date: May 2, 2008
Creator: Collaboration, The BABAR & Aubert, B.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

A Hard X-ray View on Two Distant VHE Blazars: 1ES 1101-232 and 1ES 1553+113

Description: TeV-blazars are known as prominent non-thermal emitters across the entire electromagnetic spectrum with their photon power peaking in the X-ray and TeV-band. If distant, absorption of -ray photons by the extragalactic background light (EBL) alters the intrinsic TeV spectral shape, thereby affecting the overall interpretation. Suzaku observations for two of the more distant TeV-blazars known to date, 1ES 1101-232 and 1ES 1553+113, were carried out in May and July 2006, respectively, including a … more
Date: May 2, 2008
Creator: Reimer, A.; Costamente, L.; /Stanford U., HEPL /KIPAC, Menlo Park; Madejski, G.; /KIPAC, Menlo Park /SLAC; Reimer, O. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

FOAM DENSITY SENSITIVITY STUDY FOR THE 9977 PACKAGE

Description: Two layers of insulation fill the volume of the 9977 package between the drum liner and the shell. One of these layers is composed of General Plastics FR-3716 polyurethane foam (also known as Last-A-Foam{reg_sign}), poured through fill holes in the drum bottom and foamed in place. There was concern that the density of the foam insulating layer may vary due to the manufacturing process and that variations in foam density would compromise the safety basis of the package. Thus, a structural finite… more
Date: May 2, 2008
Creator: Gorczyca, J & Tsu-Te Wu, T
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Babel Fortran 2003 Binding for Structured Data Types

Description: Babel is a tool aimed at the high-performance computing community that addresses the need for mixing programming languages (Java, Python, C, C++, Fortran 90, FORTRAN 77) in order to leverage the specific benefits of those languages. Scientific codes often rely on structured data types (structs, derived data types) to encapsulate data, and Babel has been lacking in this type of support until recently. We present a new language binding that focuses on their interoperability of C/C++ with Fortran … more
Date: May 2, 2008
Creator: Muszala, S; Epperly, T & Wang, N
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Dark Matter Capture and Annihilation on the First Stars: Preliminary Estimates

Description: Assuming that Dark Matter is dominated by WIMPs, it accretes by gravitational attraction and scattering over baryonic material and annihilates inside celestial objects, giving rise to a 'Dark Luminosity' which may potentially affect the evolution of stars. We estimate the Dark Luminosity achieved by different kinds of stars in a halo with DM properties characteristic of the ones where the first star formation episode occurs. We find that either massive, metal-free and small, galactic-like stars… more
Date: May 2, 2008
Creator: Iocco, Fabio
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Solar Water Splitting: Photocatalyst Materials Discovery and Systems Development

Description: Hydrogen promises to be an attractive transportation fuel in the post-fossil fuel era. Relatively abundant and clean burning (water being the principal byproduct), hydrogen offers the potential to significantly reduce greenhouse gas emissions. However, there are significant technical barriers that require solutions before hydrogen can be implemented in large scale. These are: · Sources (e.g. hydrocarbon, water) · Transportation · Storage Each of the aforementioned barriers carries with it impor… more
Date: May 2, 2008
Creator: McNulty, Thomas F.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Commercial Fishery Disaster Assistance

Description: This report discusses disaster relief for commercial fishery, which be provided by the federal government to assist the fishing industry when it is affected by a commercial fishery failure.
Date: May 2, 2008
Creator: Upton, Harold F.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Economic Slowdown: Issues and Policies

Description: This report first discusses the current state of the economy, including measures that have already been taken by the monetary authorities, and assesses the need for and potential consequences of fiscal stimulus. The second part of the report reviews the proposals discussed during debate on the recently enacted fiscal stimulus, both those adopted and those considered but not adopted. The various stimulus packages differed somewhat, and the report briefly describes those differences. This section… more
Date: May 2, 2008
Creator: Gravelle, Jane G.; Hungerford, Thomas L.; Labonte, Marc; Weiss, N. Eric & Whittaker, Julie M.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Cruise Ship Pollution: Background, Laws and Regulations, and Key Issues

Description: This report describes the several types of waste streams that cruise ships may discharge and emit. It identifies the complex body of international and domestic laws that address pollution from cruise ships. It then describes federal and state legislative activity concerning cruise ships in Alaskan waters and activities in a few other states, as well as current industry initiatives to manage cruise ship pollution.
Date: May 2, 2008
Creator: Copeland, Claudia
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

The Single European Payments Area (SEPA): Implementation Delays and Implications for the United States

Description: This report presents a brief background on the efforts to create the Single European Payments Area (SEPA) by the European government and the banking industry. It assesses the current electronic payments systems from the wholesale (large value) level and the retail (small value) level of payments. The report then examines the attempts to develop the pan- European automated clearinghouse system (PEACH).
Date: May 2, 2008
Creator: Eubanks, Walter W.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Navy Littoral Combat Ship (LCS) Program: Background, Oversight Issues, and Options for Congress

Description: This report details the 2007 restructuring of the Littoral Combat Ship (LCS) program, as well as various financial information relating to the program. The issue for Congress is whether to approve, reject, or modify the Navy's plans for the LCS program. The LCS program raises potential oversight issues for Congress relating to various aspects of the program, all of which are explored within this report.
Date: May 2, 2008
Creator: O'Rourke, Ronald
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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