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Linkage of the Nitrilase-Encoding Nit1C Gene Cluster to Cyanotrophy in Acinetobacter haemolyticus

Description: The Nit1C cluster is a conserved gene cluster of seven genes that confers bacterial growth on cyanide as the sole nitrogen source. Bacteria with this ability are referred to as cyanotrophs. To date, the linkage between Nit1C and cyanotrophy has only been demonstrated for environmental isolates but the cluster also exists in certain medically related bacteria. In this study, a nosocomial isolate, Acinetobacter haemolyticus ATCC 19194, carrying Nit1C also displayed the ability to grow on cyanide.… more
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Date: July 2023
Creator: Dale, Layla Momo
Partner: UNT Libraries
open access

Lind, James Meyer the Trumpet Concertos of Anthony Plog: a Performer’s Guide

Description: Anthony Plog (b. 1947) has contributed several notable works for brass instruments. He is known for writing extremely technically challenging works that contain angular melodies, fast rhythms and a large degree of chromaticism. Though his music is difficult, it also conveys intense emotions. His music for trumpet, specifically Concerto no. 1 for Trumpet, Brass Ensemble and Percussion and Concerto no. 2 for Trumpet and Orchestra, represents a zenith in his compositional development. This dissert… more
Date: August 2012
Creator: Lind, James Meyer
Partner: UNT Libraries
open access

Scattering Cross-sections of 4/1 Prolate Spheroids

Description: This is a report of the second in a projected series of experiments at North Texas State College designed for obtaining information about the microwave scattering properties of various shaped objects.
Date: 1956
Creator: Tompkins, Keith W.
Partner: UNT Libraries
open access

Pyridinium and Pyrazinium Derivatives of 2,3-Dichloro-1,4-Naphthoquinone

Description: This investigation deals with the synthesis of 2-alkylpyridine and 2-alkylpyrazine derivatives of 2,3-dichloro-1,4-naphthoquinone. These compounds will be tested for physiological activity by Parke-Davis and Company.
Date: 1956
Creator: El-Eris, Talib Mihsin
Partner: UNT Libraries
open access

Barbituric Acids. VIII. 5-substituted-5-(1-pyrrolidyl)barbituric Acids

Description: The purpose of this investigation then was the preparation of a series of 5-substituted-5-(1-pyrrolidyl)barbituric acids in which R would consist of alkyl groups ranging in size from methyl to amyl, and other groups such as phenyl and benzyl. These compounds are to be tested elsewhere for hypnotic and anticonvulsant activity.
Date: 1957
Creator: Compton, Ross Davis
Partner: UNT Libraries

Computational Modeling of Cancer-Related Mutations in DNA Repair Enzymes Using Molecular Dynamics and Quantum Mechanics/Molecular Mechanics

Description: This dissertation details the use of computational methods to understand the effect that cancer-related mutations have on proteins that complex with nucleic acids. Firstly, we perform molecular dynamics (MD) simulations of various mutations in DNA polymerase κ (pol κ). Through an experimental collaboration, we classify the mutations as more or less active than the wild type complex, depending upon the incoming nucleotide triphosphate. From these classifications we use quantum mechanics/molecula… more
Date: May 2022
Creator: Leddin, Emmett Michael
Partner: UNT Libraries
open access

NMR study of 2-ethylhexyllithium aggregate and 2- ethylhexyllithium/lithium 2-ethyl-1-hexoxide mixed aggregates.

Description: A 1H, 13C, and 6Li NMR study of 2-ethylhexyllithium showed that 2- ethylhexyllithium exists solely as a hexamer in cyclopentane solution over the temperature range from 25 to -65 °C. Furthermore, 2-ethylhexyllithium and lithium 2- ethyl-1-hexoxide were shown to form mixed aggregates when the alkoxide was formed in situ by reacting 2-ethylhexyllithium with 2-ethyl-1-hexanol. A multinuclear, variable temperature NMR study of a sample with an O:Li ratio of 0.2 led to the identification of at least… more
Date: December 2001
Creator: Petros, Robby A.
Partner: UNT Libraries

Alexander Johnson's Ni' Concerto (1994) - Concerto no. 1 for Piano and Orchestra: a Discussion of Influences from Africa, Eastern and Western Europe

Description: In the new generation of artists emerging in South Africa, Alexander Johnson is considered the most prolific young composer of his day. In a recent review in the Pretoria News, Johnson has been praised by eminent critic Paul Boekkooi as a composer who has “an ear for the exotic and knows exactly how to bring it off....” He continued by noting that his music is “mentally engrossing, pleasurable to the senses and seems refreshingly free from dogmatic formulas." Johnson writes for musicians and th… more
Access: Restricted to UNT Community Members. Login required if off-campus.
Date: August 2001
Creator: Malan, Petronel
Partner: UNT Libraries
open access

Effect of Light and Other Environmental Factors on Growth and Carotenogenesis of Corynebacterium Species Strain 7E1C

Description: This investigation studies effects of environmental factors on growth and carotenogenesis in Corynebacterium strain 7ElC. Changes in pH were found to effect growth more than carotenogenesis. However, certain nutrients or long incubation periods stimulated carotenoid formation more than growth. Dark conditions in a mineral salts-glucose medium stimulated growth, but minimized carotenogenesis. Tryptic soy broth or yeast extract elicited carotenogenesis in darkness. Although brief light exposure d… more
Date: August 1974
Creator: Howard, Marta E.
Partner: UNT Libraries
open access

An Analytical Study of Mily Alekseyevich Balakirev's Musical Style in his Early Piano and Orchestra Works: Grande Fantaisie on Russian Folk Songs and Concerto Op.1 in F# Minor.

Description: Balakirev's two early piano and orchestra works, Grande Fantaisie on Russian Folk Songs and Concerto Op. 1 in F# Minor, were composed in the middle of the nineteenth century when in Russia there were no particularly important works for piano and orchestra. Balakirev was still a teenager when he wrote these two pieces and unfortunately both remained unfinished. However the beauty and remarkable compositional achievement of these works should be highly recognized. There are six chapters in thi… more
Date: May 2007
Creator: Kim, Miyang
Partner: UNT Libraries
open access

Vincent Ludwig Persichetti's Parable for Solo Flute (Alto or Regular): A Study of Its Compositional Elements: Together with Recitals of Selected Works of Beethoven, Devienne, Handel, Hummel, Kreutzer, and Others

Description: This dissertation focuses on the first Parable of Vincent Ludwig Persichetti, written for alto flute in 1965. Persichetti spent from 1965 to 1986 (almost the last twenty years of his life) composing twenty-four additional Parables for various solo instruments, instrumental combinations, and even one in the form of an opera.
Date: December 1994
Creator: Zoloth, Alan Gary
Partner: UNT Libraries
open access

Purification, Characterization and Receptor Binding of Human Colony-Stimulating Factor-1

Description: Human colony-stimulating factor-1 (CSF-1) was purified from the serum-free conditioned medium of a human pancreatic carcinoma cell line. The four-step procedure included chromatography on DEAE Sepharose, Con A Sepharose and HPLC on phenyl column and reverse-phase C-3 column. The purity of human CSF-1 was demonstrated by sodium dodecyl sulfatepolyacrylamide gel electrophoresis (SDS—PAGE) as a single diffuse band with a molecular weight (Mr) of 42,000-50,000 and was further confirmed by a single … more
Date: May 1987
Creator: Shieh, Jae-Hung
Partner: UNT Libraries
open access

Regulation of Colony-Stimulating Factor-1 Biosynthesis

Description: Recent studies suggest that synthesis of the Colony-stimulating factor (CSF) is a well regulated process. However, the molecular mechanisms of the signal transduction of the various inducers of CSF such as monokines and lymphokines are not well understood. Using Interleukin 1 (IL-1) stimulation of CSF-1 in the MIA PaCa-2 cell line as a model system, the involvement of G-protein has been studied. The IL-1 induction of CSF-1 synthesis can be inhibited by both Pertussis toxin and Cholera toxin, wh… more
Date: May 1990
Creator: Ku, Chun-Ying
Partner: UNT Libraries
open access

Notes on the SWTPC MP-N Calculator Interface and the Calc-1 Program

Description: This interface was bought to perform floating-point arithmetic and for its function capabilities such as SIN, COS, and e^x. My application required an integer truncation function that is not performed by this calculator, so i wrote a small assembly language subroutine to do it. A potentially irritating problem is that the calculator chip does not automatically convert to scientific notation if the numbers become too big to display in floating point. The control program must keep track of the di… more
Date: May 1979
Creator: Long, Daniel Paul
Partner: UNT Libraries

An analysis of the Sonata for Trumpet and Piano by Peter Maxwell Davies, identifying the use of historical forms, and the implications for performance.

Description: The Sonata for Trumpet and Piano by Peter Maxwell Davies is one of his earliest works, and a notoriously difficult work to perform. While using serialism and other twentieth-century compositional techniques, this work also uses older historical forms, including sonata-allegro and sonata-rondo forms. An analysis of the work is presented, identifying the older historical forms, and considerations for performers when making decisions on how to perform the work are provided.
Access: Restricted to the UNT Community Members at a UNT Libraries Location.
Date: August 2006
Creator: Adduci, Kathryn James
Partner: UNT Libraries
open access

A Study of the Reduction Products of N-(4-Nitrophenacyl)-4-(1-Hexyl)pyridinium Bromide

Description: Because of the structural analogies between these compounds and several other physiologically active compounds, such as chloroamphenicol, 4,4'-diaminodiphenyl sulfone, and 2,2-bis-(p-aminophenyl)-1,1,1-trichloroethane, a more complete study of the reduction products and the sequence of catalytic reduction of N-(4-nitrophenacyl)-4-(1-hexyl)pyridinium bromide was made in this investigation.
Date: 1950
Creator: Arnwine, Bennie C.
Partner: UNT Libraries
open access

Impact of a Genetically Engineered Probiotic Therapy and IGF-1 Genomics in the PAHenu2 Mouse Model of PKU

Description: Absence of functional phenylalanine hydroxylase results in phenylketonuria (PKU). Viable treatments remain few, expensive and secondary conditions such as osteopenia occur in most PKU patients. Objective 1: Given the recently described roles of gut microbes to aid host digestion, an orally administered genetically engineered probiotic as the delivery vehicle for enzyme replacement therapy was created. The engineered probiotic, pHENOMMenal, produced phenylalanine ammonia lyase with significant… more
Date: December 2015
Creator: Durrer, Katherine Elaine
Partner: UNT Libraries
open access

Linkage of a nitrilase-containing Nit1C gene cluster to cyanide utilization in Pseudomonas fluorescens NCIMB 11764.

Description: Pseudomonas fluorescens NCIMB 11764 (Pf11764) is uniquely able to grow on the poison cyanide as its sole nitrogen source. It does so by converting cyanide oxidatively to carbon dioxide and ammonia, the latter being assimilated into cellular molecules. This requires a complex enzymatic machinery that includes nitrilase and oxygenase enzymes the nature of which are not well understood. In the course of a proteomics analysis aimed at achieving a better understanding of the proteins that may be req… more
Date: May 2009
Creator: Ghosh, Pallab
Partner: UNT Libraries
open access

Psychosocial Determinants of Diabetic Control and Satisfaction with Diabetes Care

Description: Diabetes mellitus affects 7.8% of the American population. National health statistic data and other research shows that racial/ethnic disparities exist in terms of prevalence and treatment outcomes. The present study investigated the role of patient health beliefs (i.e., locus of control, self-efficacy) and the doctor-patient relationship (e.g., satisfaction and collaboration with health care provider), as relative predictors of diabetic control (i.e., HbA1c levels) and overall satisfaction wit… more
Date: May 2011
Creator: Dzivakwe, Vanessa G.
Partner: UNT Libraries
open access

Phenotypic Analysis of Medicago truncatula NPF1.7 Over-Expressing Plants Grown under Different Nitrate Conditions

Description: Plants have many nitrate transporters; in the model legume Medicago truncatula, MtNPF1.7 is among them. MtNPF1.7 is important for M. truncatula growth and it has been established that MtNPF1.7 is a high affinity nitrate transporter. M. truncatula plants with mutations in MtNPF1.7 gene show defects during plants growth, with striking abnormalities in nodule development and root architecture. Nitrogen fixation is an energy expensive process; when legumes have sufficient bioavailable nitrogen like… more
Date: December 2017
Creator: Cai, Jingya
Partner: UNT Libraries
open access

Polystylistic Features of Schnittke's Cello Sonata (1978)

Description: Polystylism in Alfred Schnittke's music has been considered by scholars as a central aspect of his music. Although there are many published analyses of his choral music, symphonies, concerti and violin sonatas, there is no known published research for Schnittke's first cello sonata. Alfred Schnittke grew up in a culturally diverse environment influenced by many different composers and compositional styles under the restrictions of a communist Russian government. These aspects influenced the dev… more
Date: August 2010
Creator: Kleinmann, Johannes
Partner: UNT Libraries
open access

Orfeo I: an Analytic Investigation of Thea Musgrave's Work for Flute and Tape, with Performance Guide

Description: This comprehensive study of Thea Musgrave's Orfeo I is the basis for a lecture-recital performed on March 20, 1989, at the University of North Texas, as part of DMA dissertation requirements. It includes: brief bio-background of Musgrave and Orfeo; historical background of both the Orpheus legend and some landmark dramatic works based on it; general development of Musgrave's dramatic language and specific ways in which she uses it in this composition; analysis of the work; performance guide; an… more
Date: August 1989
Creator: Shotola, Marilyn W.
Partner: UNT Libraries
open access

Molecular and Functional Characterization of Medicago Truncatula Npf17 Gene

Description: Legumes are unique among plants for their ability to fix atmospheric nitrogen with the help of soil bacteria rhizobia. Medicago truncatula is used as a model legume to study different aspects of symbiotic nitrogen fixation. M. truncatula, in association with its symbiotic partner Sinorhizobium meliloti, fix atmospheric nitrogen into ammonia, which the plant uses for amino acid biosynthesis and the bacteria get reduced photosynthate in return. M. truncatula NPF1.7 previously called MtNIP/LATD is… more
Date: December 2013
Creator: Salehin, Mohammad
Partner: UNT Libraries
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