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Serotonin, Norepinephrine, and the Hypothalamic Ventromedial Nucleus: a Proposed Mechanism Mediating Hyperphagia and Obesity

Description: Serotonin has been implicated as a modulator of feeding behavior. This experiment was designed to alter brain serotonin levels through dietary means in hypothalamic ventromedial-lesioned and unlesioned rats. Daily food, water, and animal weights were measured. The purpose was to determine if VMH lesions altered the feeding pattern found in unlesioned rats. Although food intake for tryptophanenriched diets and tryptophan-deficient diets did not differ from their respective control groups, in som… more
Date: May 1981
Creator: McDermott, Kathy Howard
Partner: UNT Libraries
open access

The Fate of Benzo(a)pyrene in Tissues of Mice Exposed to Diesel Exhaust

Description: Mice were exposed to diesel exhaust for 9 months prior to evaluation for benzo(a)pyrene disposition. On the last day of exposure the mice were instilled intratracheally with tritiated-benzo(a)pyrene ([3H]BP). The mice were sacrificed at intervals of 2, 24, and 168 hours. Disappearance of radioactivity from lungs and liver was rapid and essentially linear with time. In lungs, liver, and testes; [3H]BP metabolites were found mainly as conjugates, a form readily excretable. Clearance of the hydroc… more
Date: August 1981
Creator: Loudin, Agnes D.
Partner: UNT Libraries
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