Synthetic Applications of Ketene Cycloadditions: Natural and Novel Pyrethroid Insecticides
Description:
A new synthetic route to natural and novel pyrethroid acids was developed utilizing ketene cycloaddition which is a significant improvement over existing syntheses. The newly synthesized pyrethroid acids were converted to pyrethroid esters and used to study structure-activity relationships. The cycloaddition of dichloroketene with 2,5-dimethyl-2,4-hexadiene yields (2+2) cycloaddition products, 2,2-dichlorocyclobutanones. The reductive removal of one chlorine atom from these cycloaddition produc…
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Date:
August 1985
Creator:
Ko, Jinren
Partner:
UNT Libraries