3 Matching Results

Search Results

Results: 1 - 3

Development of Biomimetic Human Lung Alveolus Chip

Description: The potential of physiologically relevant in vitro cell culture models for studying physiological and pathophysiological phenomena has been widely recognized as replacements for animal and conventional in vitro models. To create models that accurately replicate the structure and function of tissues and organs, it is essential to comprehend the biophysical and mechanical features of the extracellular matrix (ECM) and incorporate them into the in vitro cell culture models. Therefore, we first aim… more
Date: May 2023
Creator: Man, Kun
Partner: UNT Libraries

Engineering a Microfluidic Blood-Brain Barrier on a Silicon Chip

Description: The blood-brain barrier (BBB) is composed of brain microvascular endothelial cells (BMECs), pericytes, and astrocytic endfeet, which regulate the transport of molecules into and out of the brain. BMECs possess intrinsic barrier properties that limit the passage of approximately 98% of small molecules into the brain in healthy individuals. However, in some brain diseases, the BBB undergoes structural and functional alterations, which can contribute to disease progression. In this study, we aimed… more
Date: July 2023
Creator: Liu, Jiafeng
Partner: UNT Libraries

Development and Characterization of Compliant Bioelectronic Devices for Gastrointestinal Stimulation

Description: In this research, we aimed to develop thin-film devices on a polymer substrate and an alternative 3D-printed device with macroelectrodes for treating gastrointestinal (GI) conditions. First, the fabrication of thin-film devices was demonstrated on a softening thiol-ene/acrylate polymer utilizing titanium nitride (TiN) as electrode material. This was achieved by utilizing cleanroom fabrication processes such as photolithography, wet and dry etching. The functionality of the device was shown by p… more
This item is restricted from view until January 1, 2026.
Date: December 2023
Creator: Chitrakar, Chandani
Partner: UNT Libraries
Back to Top of Screen