Alpha-Adrenergic Modulation of Coronary Blood Flow and Cardiac Function During Exercise in Dogs
Description:
In the present study alpha-receptor modulation of coronary flow and cardiac function was examined in exercising dogs, chronically instrumented to measure: circumflex blood flow velocity (CFV), heart rate (HR), global left ventricular function (LVP and dP/dt Max) and regional left ventricular function (%SL and dL/dt (s)max). During exercise, local adrenergic blockade was produced by intracoronary injection of 1.0 mg phentolamine ( anon-specific alpha-antagonist) or .5 mp prazosin. Exercise sign…
more
Date:
December 1985
Creator:
Overn, Steven P. (Steven Paul)
Partner:
UNT Libraries