Local chromatin structure of heterochromatin regulates repeatedDNA stability, nucleolus structure, and genome integrity
Description:
Heterochromatin constitutes a significant portion of the genome in higher eukaryotes; approximately 30% in Drosophila and human. Heterochromatin contains a high repeat DNA content and a low density of protein-encoding genes. In contrast, euchromatin is composed mostly of unique sequences and contains the majority of single-copy genes. Genetic and cytological studies demonstrated that heterochromatin exhibits regulatory roles in chromosome organization, centromere function and telomere protectio…
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Date:
May 5, 2007
Creator:
Peng, Jamy C.
Partner:
UNT Libraries Government Documents Department