Structural Genomics of Minimal Organisms: Pipeline and Results
Description:
The initial objective of the Berkeley Structural Genomics Center was to obtain a near complete three-dimensional (3D) structural information of all soluble proteins of two minimal organisms, closely related pathogens Mycoplasma genitalium and M. pneumoniae. The former has fewer than 500 genes and the latter has fewer than 700 genes. A semiautomated structural genomics pipeline was set up from target selection, cloning, expression, purification, and ultimately structural determination. At the ti…
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Date:
September 14, 2007
Creator:
Kim, Sung-Hou; Shin, Dong-Hae; Kim, Rosalind; Adams, Paul & Chandonia, John-Marc
Partner:
UNT Libraries Government Documents Department