Engineering Cardiac Organoid Vascularization via Fluid Shear Stress and Vascular-Promoting Growth Factors
Description:
Cardiovascular disease (CVD) is the leading cause of death internationally. Efforts to decrease CVD death has been explored through stem cell technology, specifically organoid formation. Current cardiac organoid models lack the vascular networks for nutrient supply and maturation. In this study, pillar perfusion technology is used to fabricate cardiac organoids and induce vascularization via dynamic culturing and the addition of vascular promoting growth factors (GFs). In addition to this study…
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Date:
August 2022
Creator:
Huerta Gomez, Angello
Partner:
UNT Libraries