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Neurotoxic Effects of Polycyclic Aromatic Hydrocarbons in Vertebrates, from Behavioral to Cellular Levels

Description: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental toxicants found in anthropogenic mixtures such as crude oil, air pollution, vehicle exhaust, and in some natural combustion reactions. Single PAHs such as benzo[a]pyrene (BaP) also impact fish behavior when animals are exposed in early life stages and for short periods of time. Aquatic animals such as fish may encounter BaP through road runoff and oil spills, but few studies have examined the impact of aqueous exposure on adul… more
This item is restricted from view until August 1, 2025.
Date: July 2023
Creator: Dunton, Alicia D.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Air Breathing Fish: Development of Air Breathing in Bristlenose Plecos (Ancistrus cirrhosus)

Description: The bristlenose pleco (Ancistrus cirrhosus) is a species of armored catfish in the Loricariidae family that breathes air facultatively when the aquatic environment becomes hypoxic. The bristlenose pleco uses its highly vascularized stomach as an air breathing organ. The two main goals of this developmental study were to determine the size of onset of air breathing and to determine the frequency of air breathing behavior in bristlenose plecos from juveniles to adults. Developing juveniles reach … more
Date: July 2023
Creator: Crowder, Lauren Whitney
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

The Impact of Invasive Salmonids on Ecosystem Functioning in South America's Sub-Antarctic Inland and Marine Waters

Description: Invasions from coho salmon were first reported in the Cape Horn Biosphere Reserve (CHBR) in 2019 which is the most southern distribution registered to date. The CHBR is known for its high number of endemic species and unique biodiversity, such as the native fishes Galaxias maculatus and Aplochiton taeniatus. There are now three invasive salmonid species in the rivers of CHBR and are a potential threat to the native fish taxa. Stable isotope and gut content analysis were used to understand resou… more
This item is restricted from view until June 1, 2025.
Date: May 2023
Creator: Moore, Sabrina
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Hypoxia-Induced Cardiac Arrest Alters Central Nervous System Concentrations of the GLYT2 Glycine Transporter in Zebrafish (Danio rerio)

Description: Hypoxia as a stressor has physiological implications that have been a focal point for many physiological studies in recent years. In some studies, hypoxia had large effects on the organ tissue degeneration, which ultimately effects multiple ecological processes. These organ tissue studies played a part in the development of new fields like neurocardiology, a specialty that studied the relationship between the brain and the heart. This thesis focuses on how hypoxia-induced cardiac arrest alte… more
Date: July 2023
Creator: Auzenne, Alexis
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Conservation, Connectivity, and Coexistence: Understanding Corridor Efficacy in Fragmented Landscapes

Description: Conservation corridors, areas of land connecting patches of natural land cover, are frequently cited and implemented as a restorative strategy to counteract fragmentation. Current corridor ecology focuses on experimental corridor systems or designed and built conservation corridors to assess functionality. Such systems and designs are typically short, straight swaths of homogenous land cover with unambiguous transitions between patches. Quantifying the degree to which amorphous landscape config… more
Date: May 2023
Creator: Long, Amanda M.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Greater, Lesser, Guessers: A Look into the Hybridization of Greater and Lesser Prairie-Chickens

Description: My thesis focuses on the conservation consequences of the hybridization of Lesser Prairie-Chickens in Kansas. Specifically, examining how past land management practices altering the species ranges impact the distinctiveness of Lesser Prairie-Chickens. Each chapter is an individual publication that addresses if the Greater and Lesser Prairie-Chicken are distinct when applying the morphological and biological species concepts. Chapter 2 compares the evolutionary history and morphological construc… more
Date: May 2023
Creator: Stein, Carleigh M.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Combined Effects of Polycyclic Aromatic Hydrocarbons and Ultraviolet Light on Benthic and Pelagic Macroinvertebrates

Description: Crude oil commonly enters freshwater aquatic ecosystems as thin sheens forming on the water surface. Oil contains mixtures of toxic compounds called polycyclic aromatic hydrocarbons (PAHs), some of which are known to be photodynamic, increasing toxicity when combined with ultraviolet radiation. Benthic macroinvertebrate communities are commonly utilized as bioindicators, and as such rely on abundant data in literature concerning benthic macroinvertebrates' relative tolerances to a wide range of… more
This item is restricted from view until June 1, 2024.
Date: May 2023
Creator: Chapman, Abigail L.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Detection and Classification of Cancer and Other Noncommunicable Diseases Using Neural Network Models

Description: Here, we show that training with multiple noncommunicable diseases (NCDs) is both feasible and beneficial to modeling this class of diseases. We first use data from the Cancer Genome Atlas (TCGA) to train a pan cancer model, and then characterize the information the model has learned about the cancers. In doing this we show that the model has learned concepts that are relevant to the task of cancer classification. We also test the model on datasets derived independently of the TCGA cohort and s… more
Date: July 2023
Creator: Gore, Steven Lee
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

The Consequences of Early Life Stage Thyroid Suppression on Immune Function in the Fathead Minnow (Pimephales promelas)

Description: Current evidence suggests that thyroid hormones (THs) may impact development of the immune system. However, studies that explore the role of THs in immune development are limited, and the mechanisms leading to alterations in immune function are poorly understood. It is important to elucidate the role of THs in immune development given that many environmental contaminants have been shown to disrupt TH homeostasis and may also have negative impacts on the immune system. As such, the main goal of … more
Date: May 2020
Creator: Thornton Hampton, Leah Marie
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

The Effects of Probiotics on Growth, and Metabolism in Juvenile Oreochromis mossambicus (Mozambique Tilapia)

Description: Improving growth, lowering mortality rates, and having a faster turnaround to harvest is essential for the future of commercial aquaculture. The primary goal of this study was to determine if introducing a single strain probiotic Lactobacillus rhamnosus IMC 501 into the feed regimen of a commercially important aquaculture freshwater fish, Mozambique tilapia (Oreochromis mossambicus), would decrease mortality; change metabolic rates; and increase tissue wet mass (MW), standard length, growth rat… more
Date: May 2020
Creator: Anderson, Michael Earl
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Investigating the Mechanisms involved in Traffic-Generated Air Pollution: Mediated Disruption of the Blood-Brain Barrier in a Wild Type Mouse Model using a Pharmaceutical Intervention Approach

Description: This study investigated whether oxLDL and/or angiotensin (Ang) II signaling pathways mediate traffic-generated air pollution- exposure induced alterations in blood-brain barrier (BBB) integrity and permeability in a healthy wild type (C57Bl/6) mouse model; additionally, whether these outcomes are exacerbated by a high fat-diet investigated. An environmentally relevant concentration of a mixture of vehicle engine exhaust (MVE) was used. To investigate the hypotheses, 12 wk old male C57Bl/6 mice… more
Date: August 2020
Creator: Suwannasual, Usa
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

CO2 Transport and Acid-Base Status during Fluctuations in Metabolic Status in Reptiles

Description: Reptiles can often experience perturbations that greatly influence their metabolic status (e.g., temperature, exercise, digestion, and ontogeny). The most common cause of fluctuations in metabolic status in post-embryonic reptiles is arguably digestion and physical activity (which will be further referred to as exercise). The objective of this thesis is to determine the mechanisms involved in CO2 transport during digestion, determine the mechanisms that allow for the maintenance of acid-base ho… more
Date: December 2021
Creator: Conner, Justin Lawrence
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Peregrine Falcon (Falco peregrinus) Subspecies Phylogenomics Using Whole Genome Re-Sequencing

Description: Peregrine falcon subspecies taxonomy is widely debated due to uncertainty in their evolutionary history and unresolved phylogenetic reconstruction using both morphological and molecular data. Previous genetic work has shown limited support for subspecies taxonomy largely as a result of molecular markers used, potential contemporary gene flow, incomplete lineage sorting, and ancestral polymorphisms. With the advent of next-generation sequencing, the cost of generating large amounts of sequence d… more
Date: December 2020
Creator: Meeks, Garrett W.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Investigating the Effects of Traffic-Generated Air-Pollution on the Microbiome and Immune Responses in Lungs of Wildtype Mice

Description: There is increasing evidence indicating that exposure to air pollutants may be associated with the onset of several respiratory diseases such as allergic airway disease and chronic obstructive pulmonary disorder (COPD). Many lung diseases demonstrate an outgrowth of pathogenic bacteria belonging to the Proteobacteria phylum, and the incidence of occurrence of these diseases is higher in heavily polluted regions. Within the human body, the lungs are among the first to be exposed to the harmful e… more
Date: December 2020
Creator: Daniel, Sarah
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Alterations in the Expression of Proteins Associated with Non-Alcoholic Fatty Liver Disease Observed in the Liver of the C57Bl/6 Wild-Type Male Mouse in Response to Exposure of Mixed Vehicle Emissions and/or High Fat Diet Consumption

Description: Recent epidemiological studies have demonstrated a correlation between the manifestation of non-alcoholic fatty liver disease (NAFLD) and ambient air pollution levels, which is exacerbated by the presence of other risk factors, such as diabetes, dyslipidemia, obesity, and hypertension. We investigated the hypothesis that exposure to a mixture of gasoline and diesel engine emissions (MVE) coupled with the concurrent consumption of a high-fat (HF) diet promotes the development of a NAFLD phenotyp… more
This item is restricted from view until January 1, 2025.
Date: December 2022
Creator: Schneider, Leah Jayne
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Flow-Recruitment Relationships of Smallmouth Buffalo (Ictiobus bubalus) in Three Texas River Basins

Description: This project focused on the relationship between instream flows and smallmouth buffalo (Ictiobus bubalus) recruitment in the Gulf Coastal Plain of Texas. The flow regime is the dominant factor in lotic systems and, consequently, the relationship between instream flows, including impacts to natural flow regimes, and life-history is a subject of growing interest. Smallmouth buffalo is a good model to investigate the relationship between river flows and variable interannual recruitment success of … more
Date: August 2021
Creator: Reeves, Cole Griffin
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Metabolic Responses to Crude Oil during Very Early Development in the Zebrafish (Danio rerio)

Description: The present study sought to determine some morphological and physiological critical windows during very early development in zebrafish exposed to crude oil. I hypothesized that exposed zebrafish would present a decrease in survival rate and body mass, and an increase in routine oxygen consumption (ṀO2), and critical oxygen tension (PCrit). To test these hypotheses, zebrafish were acutely exposed (24 h) during different days of development (1 to 6 days post-fertilization, dpf) to different conce… more
Date: August 2020
Creator: Vazquez Roman, Karem Nathalie
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Multi-Level Effects of Oxygen Exposure in Endothermic Insects

Description: This dissertation examined the phenotypic plasticity of endothermic, flight and respiratory physiology in response to developmental oxygen exposure in the moth Manduca sexta. Development in both 10% O2 hypoxia and 30% O2 hyperoxia treatments were used to look at the physiological consequence on both ends of the oxygen spectrum. Hypoxic insects reached smaller sizes as adults and had longer pupation lengths than controls. Hyperoxic insects were larger at the end of the larval stage, had increase… more
Date: August 2022
Creator: Wilmsen, Sara M
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Analysis of the Accumulation, Toxic Effects, and Risk of Persistent Organic Pollutants in Pinnipeds

Description: The present studies determine the accumulation of persistent organic pollutants (POPs) in three pinniped species, evaluate the relationship with relevant biomarkers of exposure, and calculate toxic effect thresholds. Stranded harp and hooded seals were found to be accumulating PBDEs at levels which could pose a based on threshold levels determined in this study. Northern fur seals are accumulating all three classes of POPs (PCBs, PBDEs, and OCPs) with significant relationships being seen with b… more
Date: August 2021
Creator: Soulen, Brianne K
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Production and Optimization of Para-Hydroxybenzoic Acid (pHBA) in Algae Using Metabolic Engineering and Genomics Approaches

Description: Microalgae being photosynthetic and having quick growth cycles can prove to be excellent candidates as biofactories for the production of aromatic compounds like para-hydroxybenzoic acid (pHBA) that act as a monomer in liquid crystal polymers. We developed transgenic lines of the model alga Chlamydomonas reinhardtii by performing nuclear transformation using electroporation. The transgenic cell lines expressed the ubiC gene that utilized chorismate from the shikimate pathway as a substrate to p… more
Date: December 2021
Creator: Saxena, Garima Girish
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

A Genetic Assessment of the Mating System of a Suburban Red-Shouldered Hawk Population in Southwest Ohio

Description: Considering the high reproductive investment of the social male and the cost to the female of losing this benefit by soliciting copulations outside the social pair bond, it is expected that most raptor populations would exhibit low to no occurrence of extra-pair paternity (EPP). This holds true for the majority of raptor species studied to date with only one exception of an urban Cooper's hawk (Accipiter cooperii) study which reported an unexpectedly high extra-pair young frequency of 19.29%. I… more
Date: May 2021
Creator: Wrona, Anna Maria
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Sociality in Harris's Hawks Revisited: Patterns of Reproductive Output and Delayed Dispersal

Description: In the lower Rio Grande Valley of south Texas, more than half the nesting groups of Harris's hawks (Parabuteo unicinctus) include at least one auxiliary group member in addition to a breeding pair. To provide further insight into cooperatively breeding raptors, I evaluated sociality in Harris's hawks through the dual benefits framework. I explored the formation, structure, and stability of cooperative group formation across a spatially variable study area, which includes high levels of urbaniza… more
Date: August 2021
Creator: Gibbons, Andrea L
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

A Test of the Female Mimicry Hypothesis in Painted Buntings (Passerina ciris)

Description: While female mimicry and lower status signaling hypotheses of delayed plumage maturation have received much discussion in the literature, the experimental tests of these hypotheses have been infrequent. Those experimental tests often use a simulated intruder method with artificial model intruders rather than using live conspecific birds as intruders. Subadult male painted buntings (Passerina ciris) possess delayed plumage maturation where they appear visually identical to adult females during t… more
Date: May 2021
Creator: Gurley, Christine E
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Migration Tracking, Survival, and Pairing Behavior of American Kestrels Wintering in North Central Texas

Description: The American Kestrel (Falco sparverius) is the smallest and most abundant falcon in North America with a wide geographic range. Unfortunately, surveys have suggested that some kestrel populations have been in decline since the 1950s, though the nominal causes of this decline are unknown. Migratory movement patterns and connectivity have yet to be established for any population of migratory kestrels. In Chapter 2, I investigated methods for attaching migration trackers to kestrels. Specifically,… more
Date: December 2022
Creator: Biles, Kelsey S
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
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