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Form and Function of the Vertebrate and Invertebrate Blood-Brain Barriers

Description: Article reviewing blood-brain barriers (BBBs) in their various forms in both invertebrates and vertebrates, with an emphasis on the function, evolution, and conditional relevance of popular animal models such as the fruit fly and the zebrafish to mammalian BBB research.
Date: November 9, 2021
Creator: Dunton, Alicia D.; Göpel, Torben; Ho, Dao H. & Burggren, Warren W.
Item Type: Refine your search to only Article
Partner: UNT College of Science
open access

Crucial Development: Criticality Is Important to Cell-to-Cell Communication and Information Transfer in Living Systems

Description: This article is the fourth paper of the Special Issue Memory and Criticality. It bridges the the theoretical debate on the role of memory and criticality discussed in the three earlier manuscripts, with a review of key concepts in biology and focus on cell-to-cell communication in organismal development. The authors suggest that in conjunction with morphogenetic gradients, there exist gradients of information transfer creating cybernetic loops of stability and disorder, setting the stage for ad… more
Date: August 31, 2021
Creator: Hunt von Herbing, Ione; Tonello, Lucio; Benfatto, Maurizio; Pease, April & Grigolini, Paolo
Item Type: Refine your search to only Article
Partner: UNT College of Science
open access

Editorial: Microbial C1 Metabolism and Biotechnology

Description: This article is an editorial on the research topic Microbial C1 Metabolism and Biotechnology. This special topic presents studies focused on the fundamental aspects of C1 metabolism in diverse microbial systems with the ability to convert anthropogenic greenhouse gases into valuable products.
Date: August 27, 2021
Creator: Xiong, Wei; Kalyuzhnaya, Marina G. & Henard, Calvin
Item Type: Refine your search to only Article
Partner: UNT College of Science
open access

Ecological Responses to Severe Flooding in Coastal Ecosystems: Determining the Vegetation Response to Hurricane Harvey within a Texas Coast Salt Marsh

Description: Vegetative health was measured both before and after Hurricane Harvey using remotely sensed vegetation indices on the coastal marshland surrounding Galveston Island's West Bay. Data were recorded on a monthly basis following the hurricane from September of 2005 until September of 2019 in order to document the vegetation response to this significant disturbance event. Both initial impact and recovery were found to be dependent on a variety of factors, including elevation zone, spatial proximity … more
Date: August 2021
Creator: Hudman, Kenneth Russell
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

The Development of Potential Therapeutic Anti-Myosin S2 Peptides that Modulate Contraction and Append to the Heart Homing Adduct Tannic Acid without Noticeable Effect on Their Functions

Description: This dissertation aimed to explore the S2 region with an attempt to modulate its elasticity in order to tune the contraction output. Two peptides, the stabilizer and destabilizer, showed high potential in modifying the S2 region at the cellular level, thus they were prepared for animal model testing. In this research, (i) S2 elasticity was studied, and the stabilizer and destabilizer peptides were built to tune contraction output through modulating S2 flexibility; (ii) the peptides were attache… more
Date: May 2021
Creator: Qadan, Motamed
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Studies on the Fibrinolytic Pathway in Zebrafish

Description: Fibrinolysis pathway is an important mechanism for dissolution of fibrin clot by the action of plasmin which is formed from plasminogen, a zymogen via the action of plasminogen activators, i.e. tissue plasminogen activator and urinary plasminogen activator. The regulation of fibrinolysis system in vivo is maintained by plasminogen activators and natural inhibitors i.e. α2-antiplasmin, α2-macroglobulin, Thrombin-activatable fibrinolysis inhibitor (TAFI) and plasminogen activator inhibitor 1 and … more
Date: August 2021
Creator: Gill, Jaspreet Kaur
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

LDIP cooperates with SEIPIN and LDAP to facilitate lipid droplet biogenesis in Arabidopsis

Description: Article showing that a recently identified protein termed LD-associated protein [LDAP]-interacting protein (LDIP) works together with both endoplasmic reticulum-localized SEIPIN and the LD-coat protein LDAP to facilitate LD formation in Arabidopsis thaliana. The data is discussed in the context of a new model for LD biogenesis in plant cells with evolutionary connections to LD biogenesis in other eukaryotes.
Date: June 9, 2021
Creator: Pyc, Michal; Gidda, Satinder K.; Seay, Damien C.; Esnay, Nicolas; Kretzschmar, Franziska K.; Cai, Yingqi et al.
Item Type: Refine your search to only Article
Partner: UNT College of Science
open access

Re-engineering Plant Phenylpropanoid Metabolism With the Aid of Synthetic Biosensors

Description: Article that provides a brief overview of current research on synthetic biology and metabolic engineering approaches to control phenylpropanoid synthesis and phenylpropanoid-related biosensors, advocating for the use of biosensors and genetic circuits as a step forward in plant synthetic biology to develop autonomously-controlled phenylpropanoid-producing plant biofactories.
Date: September 16, 2021
Creator: Ferreira, Savio S. & Antunes, Mauricio S.
Item Type: Refine your search to only Article
Partner: UNT College of Science
open access

CO2 Transport and Acid-Base Status during Fluctuations in Metabolic Status in Reptiles

Description: Reptiles can often experience perturbations that greatly influence their metabolic status (e.g., temperature, exercise, digestion, and ontogeny). The most common cause of fluctuations in metabolic status in post-embryonic reptiles is arguably digestion and physical activity (which will be further referred to as exercise). The objective of this thesis is to determine the mechanisms involved in CO2 transport during digestion, determine the mechanisms that allow for the maintenance of acid-base ho… more
Date: December 2021
Creator: Conner, Justin Lawrence
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Flow-Recruitment Relationships of Smallmouth Buffalo (Ictiobus bubalus) in Three Texas River Basins

Description: This project focused on the relationship between instream flows and smallmouth buffalo (Ictiobus bubalus) recruitment in the Gulf Coastal Plain of Texas. The flow regime is the dominant factor in lotic systems and, consequently, the relationship between instream flows, including impacts to natural flow regimes, and life-history is a subject of growing interest. Smallmouth buffalo is a good model to investigate the relationship between river flows and variable interannual recruitment success of … more
Date: August 2021
Creator: Reeves, Cole Griffin
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Analysis of the Accumulation, Toxic Effects, and Risk of Persistent Organic Pollutants in Pinnipeds

Description: The present studies determine the accumulation of persistent organic pollutants (POPs) in three pinniped species, evaluate the relationship with relevant biomarkers of exposure, and calculate toxic effect thresholds. Stranded harp and hooded seals were found to be accumulating PBDEs at levels which could pose a based on threshold levels determined in this study. Northern fur seals are accumulating all three classes of POPs (PCBs, PBDEs, and OCPs) with significant relationships being seen with b… more
Date: August 2021
Creator: Soulen, Brianne K
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Production and Optimization of Para-Hydroxybenzoic Acid (pHBA) in Algae Using Metabolic Engineering and Genomics Approaches

Description: Microalgae being photosynthetic and having quick growth cycles can prove to be excellent candidates as biofactories for the production of aromatic compounds like para-hydroxybenzoic acid (pHBA) that act as a monomer in liquid crystal polymers. We developed transgenic lines of the model alga Chlamydomonas reinhardtii by performing nuclear transformation using electroporation. The transgenic cell lines expressed the ubiC gene that utilized chorismate from the shikimate pathway as a substrate to p… more
Date: December 2021
Creator: Saxena, Garima Girish
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

A Genetic Assessment of the Mating System of a Suburban Red-Shouldered Hawk Population in Southwest Ohio

Description: Considering the high reproductive investment of the social male and the cost to the female of losing this benefit by soliciting copulations outside the social pair bond, it is expected that most raptor populations would exhibit low to no occurrence of extra-pair paternity (EPP). This holds true for the majority of raptor species studied to date with only one exception of an urban Cooper's hawk (Accipiter cooperii) study which reported an unexpectedly high extra-pair young frequency of 19.29%. I… more
Date: May 2021
Creator: Wrona, Anna Maria
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Sociality in Harris's Hawks Revisited: Patterns of Reproductive Output and Delayed Dispersal

Description: In the lower Rio Grande Valley of south Texas, more than half the nesting groups of Harris's hawks (Parabuteo unicinctus) include at least one auxiliary group member in addition to a breeding pair. To provide further insight into cooperatively breeding raptors, I evaluated sociality in Harris's hawks through the dual benefits framework. I explored the formation, structure, and stability of cooperative group formation across a spatially variable study area, which includes high levels of urbaniza… more
Date: August 2021
Creator: Gibbons, Andrea L
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

A Test of the Female Mimicry Hypothesis in Painted Buntings (Passerina ciris)

Description: While female mimicry and lower status signaling hypotheses of delayed plumage maturation have received much discussion in the literature, the experimental tests of these hypotheses have been infrequent. Those experimental tests often use a simulated intruder method with artificial model intruders rather than using live conspecific birds as intruders. Subadult male painted buntings (Passerina ciris) possess delayed plumage maturation where they appear visually identical to adult females during t… more
Date: May 2021
Creator: Gurley, Christine E
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Multiple Dimensions of Fish Functional Traits, Trait Relationships, and Associations with Community Structure and Dynamics

Description: Trait-based approaches are useful in ecological research because of their potential ability to predict species responses from patterns present in the community and to infer mechanisms driving community assembly. Current approaches for fishes are lacking traits across all five fundamental niche dimensions (i.e. habitat, life history, trophic, metabolic and defense). This study quantified a broad range of fish functional traits across all five niche dimensions (commonly used traits and novel trai… more
Date: December 2021
Creator: Harried, Brittany Lee
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Breeding Ecology and Migratory Connectivity of Passerines in the World's Southernmost Forests

Description: In the extensive and remote sub-Antarctic forests of South America, birds are the dominant terrestrial vertebrates. Despite considerable efforts to understand the ecology of birds breeding in these forests, our current knowledge for many species is still incomplete. During three breeding seasons (2014 – 2017), I studied the breeding ecology of the five most abundant open-cup forest-dwelling passerines in the sub-Antarctic forest of Navarino Island, Chile (55°04′S, 67°40′W). There were differenc… more
Date: May 2021
Creator: Jara Millar, Rocio Fernanda
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Benefits of Probiotics on Mortality, Growth Performance, Physiological Condition and Gut Histomophology of Juvenile Red Drum (Sciaenops ocellatus)

Description: Results from the present study found for the first time that the use of bacterial strains of Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium thermophilum, and Enterococcus faecium from the commercial product PrimaLac® had the potential to act as a possible probiotic for juvenile red drum. The addition of PrimaLac® probiotics [whether as a water-soluble probiotic (WSP) or in a probiotic enhanced starter feed (PESF)] reduced mortality (%M), enhanced growth rates (MW, LT, SGR, and … more
Date: May 2021
Creator: Busby, Wren Adell
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Manipulation of Lipid Droplet Biogenesis for Enhanced Lipid Storage in Arabidopsis thaliana and Nicotiana benthamiana

Description: In this study, I examined the use of mouse (Mus musculus) Fat Specific Protein 27 (FSP27) ectopically expressed in Arabidopsis thaliana and Nicotiana benthamiana as a means to increase lipid droplet (LD) presence in plant tissues. In mammalian cells, this protein induces cytoplasmic LD clustering and fusion and helps prevent breakdown of LDs contributing to the large, single LD that dominates adipocytes. When expressed in Arabidopsis thaliana and Nicotiana benthamiana, FSP27 retained its functi… more
Date: December 2021
Creator: Price, Ann Marie
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Dietary Polyphenol and Methylsulfonylmethane Supplementation Improves Immune, DAMP Signaling, and Inflammatory Responses During Recovery From All-Out Running Efforts

Description: This article presents a study with the purpose to determine the effect of dietary supplementation with optimized curcumin, pomegranate ellagitannins, and MSM (R + MSM) on immune-associated mRNA during early recovery (i.e., up to 8 h post-exercise) following all-out running efforts (5-km, 10-km, and 21.1-km). The results demonstrate that supplementation with a combination of optimized curcumin, pomegranate ellagitannins, and methylsulfonylmethane resulted in changes that may improve biological r… more
Date: August 31, 2021
Creator: McFarlin, Brian K.; Hill, David W.; Vingren, Jakob L.; Curtis, John H. & Tanner, Elizabeth A.
Item Type: Refine your search to only Article
Partner: University of North Texas

Multi-Omics Based Investigation of Distinct Early Oxidative Stress Responses of Saccharomyces cerevisiae to Various Oxidants

Description: The early signaling mechanism(s) that control oxidant perception and signal transduction leading to activation of the antioxidant defense response and survival mechanisms tailored toward specific oxidative insult remains unknown. Here, we identified early changes in metabolome and proteome of S. cerevisiae in response to hydrogen peroxide, menadione, cumene hydroperoxide, and diamide. Firstly, global untargeted LC–MS/MS analysis allowed us to identify 196 proteins in response to hydrogen peroxi… more
Date: May 2021
Creator: Pandey, Prajita
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Probabilistic Modeling for Whole Metagenome Profiling

Description: To address the shortcomings in existing Markov model implementations in handling large amount of metagenomic data with comparable or better accuracy in classification, we developed a new algorithm based on pseudo-count supplemented standard Markov model (SMM), which leverages the power of higher order models to more robustly classify reads at different taxonomic levels. Assessment on simulated metagenomic datasets demonstrated that overall SMM was more accurate in classifying reads to their res… more
Date: May 2021
Creator: Burks, David
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Ozone Pollution Monitoring and Population Vulnerability in Dallas-Ft. Worth: A Decision Support Approach

Description: In urban environments, ozone air pollution, poses significant risks to respiratory health. Fixed site monitoring is the primary method of measuring ozone concentrations for health advisories and pollutant reduction, but the spatial scale may not reflect the current population distribution or its future growth. Moreover, formal methods for the placement of ozone monitoring sites within populations potentially omit important spatial criteria, producing monitoring locations that could unintention… more
Date: August 2021
Creator: Northeim, Kari M.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

Biomonitoring at Dallas-Fort Worth International Airport: Relating Watershed Land Use with Aquatic Life Use

Description: The Dallas-Fort Worth International (DFW) Airport is located in a densely urbanized area with one of the fastest-growing populations in the U.S.A. The airport property includes a large tract of "protected" riparian forest that is unique to the urban surroundings. This dissertation explores variables that influence the benthic macroinvertebrate community structure found in urbanized prairie streams that were initially assessed by the University of North Texas (UNT) Benthic Ecology Lab during fou… more
Date: August 2021
Creator: Harlow, Megann Mae Lewis
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
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