Method for detecting and diagnosing disease caused by pathological protein aggregation
Description:
A method is provided for detecting pathological macromolecules in a patient, comprising obtaining body fluid from the patient, pretreating the body fluid, subjecting the pretreated body fluid to size-exclusion chromatography to create an excluded fluid, and analyzing the excluded fluid to detect macromolecules having a predetermined molecular weight. The method also allows for comparing elution spectra with reference spectra of suspect pathologic proteins.
Date:
December 31, 1994
Creator:
Stevens, F. J.
Partner:
UNT Libraries Government Documents Department